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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
13.64
Human Site:
Y268
Identified Species:
23.08
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
Y268
G
R
I
T
K
W
K
Y
P
F
P
K
E
T
E
Chimpanzee
Pan troglodytes
XP_511585
968
108684
N272
N
L
P
K
H
R
E
N
V
I
P
A
D
S
E
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
Y361
G
R
I
T
K
W
K
Y
P
F
P
K
E
T
E
Dog
Lupus familis
XP_853409
975
109686
Y268
G
R
I
T
K
W
K
Y
P
F
P
K
E
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
Y270
G
R
I
T
K
W
K
Y
P
F
P
K
E
T
E
Rat
Rattus norvegicus
XP_573211
965
109012
E265
Y
P
F
P
K
E
T
E
A
K
S
K
L
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
A263
K
Y
S
T
S
L
Y
A
S
P
S
M
V
H
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
Q273
R
L
I
K
W
N
Y
Q
A
V
Q
Q
L
S
S
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
K262
N
T
Q
S
H
T
M
K
W
T
Y
Q
F
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
A264
D
L
S
S
P
V
V
A
A
F
L
L
G
P
D
Honey Bee
Apis mellifera
XP_392044
968
110555
E263
I
A
V
Y
I
V
R
E
D
G
L
L
T
V
P
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
P276
I
F
T
V
D
Q
W
P
T
V
L
G
V
N
A
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
N288
G
E
Y
P
T
W
R
N
Q
L
L
G
Y
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
K268
V
D
C
S
P
E
E
K
I
K
L
Q
E
C
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
13.3
100
100
N.A.
100
20
N.A.
13.3
N.A.
6.6
6.6
N.A.
6.6
0
0
20
P-Site Similarity:
100
33.3
100
100
N.A.
100
20
N.A.
13.3
N.A.
20
26.6
N.A.
20
13.3
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
15
22
0
0
8
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
8
0
0
8
0
0
0
8
0
0
0
8
0
8
% D
% Glu:
0
8
0
0
0
15
15
15
0
0
0
0
36
0
50
% E
% Phe:
0
8
8
0
0
0
0
0
0
36
0
0
8
0
0
% F
% Gly:
36
0
0
0
0
0
0
0
0
8
0
15
8
0
0
% G
% His:
0
0
0
0
15
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
15
0
36
0
8
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
8
0
0
15
36
0
29
15
0
15
0
36
0
0
15
% K
% Leu:
0
22
0
0
0
8
0
0
0
8
36
15
15
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
15
0
0
0
0
8
0
15
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
15
15
0
0
8
29
8
36
0
0
8
15
% P
% Gln:
0
0
8
0
0
8
0
8
8
0
8
22
0
0
0
% Q
% Arg:
8
29
0
0
0
8
15
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
15
22
8
0
0
0
8
0
15
0
0
15
8
% S
% Thr:
0
8
8
36
8
8
8
0
8
8
0
0
8
50
0
% T
% Val:
8
0
8
8
0
15
8
0
8
15
0
0
15
8
0
% V
% Trp:
0
0
0
0
8
36
8
0
8
0
0
0
0
0
0
% W
% Tyr:
8
8
8
8
0
0
15
29
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _