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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
16.36
Human Site:
Y354
Identified Species:
27.69
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
Y354
K
S
K
N
K
L
N
Y
L
R
N
Y
W
L
L
Chimpanzee
Pan troglodytes
XP_511585
968
108684
Q358
M
H
Q
Q
Q
Q
L
Q
H
Q
Q
F
Q
K
E
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
Y447
K
S
K
N
K
L
N
Y
L
R
N
Y
W
L
L
Dog
Lupus familis
XP_853409
975
109686
Y354
K
G
K
N
K
L
N
Y
L
R
N
Y
W
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
Y356
K
G
K
S
K
L
N
Y
L
R
N
Y
W
L
L
Rat
Rattus norvegicus
XP_573211
965
109012
L351
Y
L
R
N
Y
W
L
L
I
G
H
H
E
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
N349
K
I
L
E
R
F
P
N
S
L
P
K
R
A
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
L359
V
I
S
A
H
Q
W
L
L
I
G
H
H
E
L
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
S348
Y
P
P
G
S
S
S
S
L
Q
N
Q
W
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
Q350
T
G
D
Q
N
S
N
Q
E
T
D
P
R
T
I
Honey Bee
Apis mellifera
XP_392044
968
110555
P349
K
N
D
N
G
N
V
P
L
S
D
T
Y
N
N
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
S362
I
I
R
N
I
P
P
S
I
T
H
K
T
S
D
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
E374
L
I
L
L
G
Y
H
E
L
P
A
N
S
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
I354
V
S
P
T
F
P
G
I
I
V
G
L
F
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
0
100
93.3
N.A.
86.6
6.6
N.A.
6.6
N.A.
13.3
33.3
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
33.3
N.A.
13.3
N.A.
20
46.6
N.A.
20
40
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
15
0
0
8
8
% D
% Glu:
0
0
0
8
0
0
0
8
8
0
0
0
8
8
15
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
8
8
0
0
% F
% Gly:
0
22
0
8
15
0
8
0
0
8
15
0
0
0
0
% G
% His:
0
8
0
0
8
0
8
0
8
0
15
15
8
0
0
% H
% Ile:
8
29
0
0
8
0
0
8
22
8
0
0
0
8
8
% I
% Lys:
43
0
29
0
29
0
0
0
0
0
0
15
0
8
0
% K
% Leu:
8
8
15
8
0
29
15
15
58
8
0
8
0
36
43
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
43
8
8
36
8
0
0
36
8
0
8
8
% N
% Pro:
0
8
15
0
0
15
15
8
0
8
8
8
0
0
8
% P
% Gln:
0
0
8
15
8
15
0
15
0
15
8
8
8
0
0
% Q
% Arg:
0
0
15
0
8
0
0
0
0
29
0
0
15
0
0
% R
% Ser:
0
22
8
8
8
15
8
15
8
8
0
0
8
8
0
% S
% Thr:
8
0
0
8
0
0
0
0
0
15
0
8
8
15
0
% T
% Val:
15
0
0
0
0
0
8
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
8
8
0
0
0
0
0
36
0
0
% W
% Tyr:
15
0
0
0
8
8
0
29
0
0
0
29
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _