KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
31.82
Human Site:
Y652
Identified Species:
53.85
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
Y652
C
A
A
T
L
Q
E
Y
V
E
Q
K
D
F
A
Chimpanzee
Pan troglodytes
XP_511585
968
108684
R637
H
S
L
N
I
G
E
R
L
H
F
T
R
P
A
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
Y745
C
A
A
T
L
Q
E
Y
V
E
Q
K
D
F
A
Dog
Lupus familis
XP_853409
975
109686
Y650
C
A
A
T
L
Q
E
Y
V
E
Q
K
D
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
Y652
C
A
A
T
L
Q
E
Y
V
E
Q
K
D
F
A
Rat
Rattus norvegicus
XP_573211
965
109012
Y640
C
A
A
T
L
Q
E
Y
V
E
Q
K
D
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
Y613
C
T
A
T
L
Q
E
Y
V
E
Q
K
D
F
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
Y643
C
A
A
T
L
Q
E
Y
I
K
N
P
E
F
H
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
Y610
C
A
A
T
L
Q
Q
Y
V
E
D
P
S
C
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
Y629
C
A
A
T
L
Q
D
Y
T
E
G
D
R
S
L
Honey Bee
Apis mellifera
XP_392044
968
110555
A619
R
Q
A
T
S
G
L
A
H
L
H
L
L
D
I
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
G623
I
M
K
Q
A
T
D
G
L
A
H
L
H
A
S
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
F671
C
T
A
T
L
Q
E
F
V
H
D
R
G
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
L755
C
N
L
N
L
Q
D
L
V
E
S
K
N
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
86.6
N.A.
60
60
N.A.
53.3
13.3
0
46.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
93.3
N.A.
80
66.6
N.A.
60
13.3
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
79
0
8
0
0
8
0
8
0
0
0
8
43
% A
% Cys:
79
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
22
0
0
0
15
8
43
8
0
% D
% Glu:
0
0
0
0
0
0
65
0
0
65
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
50
8
% F
% Gly:
0
0
0
0
0
15
0
8
0
0
8
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
15
15
0
8
0
8
% H
% Ile:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
0
8
0
50
0
0
0
% K
% Leu:
0
0
15
0
79
0
8
8
15
8
0
15
8
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
15
0
0
0
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
15
0
8
8
% P
% Gln:
0
8
0
8
0
79
8
0
0
0
43
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
8
15
8
0
% R
% Ser:
0
8
0
0
8
0
0
0
0
0
8
0
8
8
22
% S
% Thr:
0
15
0
79
0
8
0
0
8
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
65
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _