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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
16.67
Human Site:
Y83
Identified Species:
28.21
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
Y83
D
P
N
D
G
S
L
Y
T
L
G
S
K
N
N
Chimpanzee
Pan troglodytes
XP_511585
968
108684
H80
D
V
D
Y
K
M
S
H
F
V
S
N
G
D
G
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
Y176
D
P
N
D
G
S
L
Y
T
L
G
S
K
N
N
Dog
Lupus familis
XP_853409
975
109686
Y83
D
P
N
D
G
S
L
Y
T
L
G
G
K
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
Y85
D
P
N
D
G
S
L
Y
T
L
G
G
K
N
N
Rat
Rattus norvegicus
XP_573211
965
109012
L83
G
G
K
N
N
E
G
L
T
K
L
P
F
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
D81
A
S
P
C
R
S
S
D
G
I
L
Y
M
G
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
Y88
D
P
S
D
G
S
L
Y
I
L
G
G
R
N
K
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
G81
D
G
S
L
Y
V
L
G
G
K
R
K
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
D82
I
R
W
T
I
A
D
D
P
P
I
V
A
E
H
Honey Bee
Apis mellifera
XP_392044
968
110555
D81
N
I
L
W
R
Q
N
D
E
P
I
V
K
V
P
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
L95
P
N
P
L
D
G
S
L
Y
V
L
K
N
S
S
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
L105
P
D
P
T
D
G
T
L
Y
V
L
G
P
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
N83
L
S
S
Y
P
T
P
N
L
L
N
T
A
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
6.6
N.A.
6.6
N.A.
66.6
13.3
N.A.
0
6.6
0
0
P-Site Similarity:
100
40
100
93.3
N.A.
93.3
13.3
N.A.
13.3
N.A.
80
26.6
N.A.
13.3
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
8
8
36
15
0
8
22
0
0
0
0
0
15
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% F
% Gly:
8
15
0
0
36
15
8
8
15
0
36
29
8
22
15
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
8
0
0
0
8
8
15
0
0
0
8
% I
% Lys:
0
0
8
0
8
0
0
0
0
15
0
15
36
0
15
% K
% Leu:
8
0
8
15
0
0
43
22
8
43
29
0
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
29
8
8
0
8
8
0
0
8
8
8
36
36
% N
% Pro:
15
36
22
0
8
0
8
0
8
15
0
8
8
0
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
15
0
0
0
0
0
8
0
8
0
0
% R
% Ser:
0
15
22
0
0
43
22
0
0
0
8
15
0
8
8
% S
% Thr:
0
0
0
15
0
8
8
0
36
0
0
8
0
8
0
% T
% Val:
0
8
0
0
0
8
0
0
0
22
0
15
0
8
0
% V
% Trp:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
8
0
0
36
15
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _