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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F6
All Species:
10.61
Human Site:
S132
Identified Species:
23.33
UniProt:
O75461
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75461
NP_937987.2
281
31844
S132
R
W
I
G
S
D
L
S
N
F
G
A
V
P
Q
Chimpanzee
Pan troglodytes
XP_001159434
249
28084
L111
A
V
P
Q
Q
K
K
L
Q
E
E
L
S
D
L
Rhesus Macaque
Macaca mulatta
XP_001088811
281
31712
S132
R
W
I
G
S
D
L
S
N
F
G
A
V
P
Q
Dog
Lupus familis
XP_852463
282
31896
S132
R
W
I
G
S
D
L
S
N
F
G
A
V
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
O54917
272
30864
N132
R
W
I
G
S
D
L
N
N
F
G
A
A
P
Q
Rat
Rattus norvegicus
NP_001094187
272
30777
N132
R
W
I
G
S
D
L
N
N
F
G
A
A
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505549
547
60104
D210
Q
W
V
G
T
D
L
D
N
M
G
R
R
V
L
Chicken
Gallus gallus
Q90977
403
43534
A173
Q
W
L
G
S
Q
V
A
A
G
A
S
S
R
Q
Frog
Xenopus laevis
NP_001081986
429
46399
P211
Q
W
M
G
C
S
L
P
D
D
G
G
N
L
A
Zebra Danio
Brachydanio rerio
NP_001025315
405
45233
L251
Q
W
M
S
S
T
P
L
S
S
F
G
S
Q
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
S200
Q
W
K
G
A
S
S
S
V
A
I
H
P
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
98.5
95
N.A.
83.9
85
N.A.
35.4
31.7
31.9
33
N.A.
N.A.
N.A.
N.A.
33.6
Protein Similarity:
100
88.2
98.9
96.8
N.A.
89.6
90
N.A.
43.5
47.3
46.1
46.9
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
0
100
100
N.A.
86.6
86.6
N.A.
40
26.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
0
100
100
N.A.
93.3
93.3
N.A.
60
60
46.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
10
10
10
10
46
19
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
55
0
10
10
10
0
0
0
10
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
46
10
0
0
0
0
% F
% Gly:
0
0
0
82
0
0
0
0
0
10
64
19
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
46
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
64
19
0
0
0
10
0
10
19
% L
% Met:
0
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
55
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
10
10
0
0
0
0
10
46
0
% P
% Gln:
46
0
0
10
10
10
0
0
10
0
0
0
0
10
55
% Q
% Arg:
46
0
0
0
0
0
0
0
0
0
0
10
10
10
0
% R
% Ser:
0
0
0
10
64
19
10
37
10
10
0
10
28
0
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
10
0
10
0
0
0
28
10
0
% V
% Trp:
0
91
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _