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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F6
All Species:
24.24
Human Site:
Y70
Identified Species:
53.33
UniProt:
O75461
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75461
NP_937987.2
281
31844
Y70
R
F
D
V
S
L
V
Y
L
T
R
K
F
M
D
Chimpanzee
Pan troglodytes
XP_001159434
249
28084
S49
K
F
M
D
L
V
R
S
A
P
G
G
I
L
D
Rhesus Macaque
Macaca mulatta
XP_001088811
281
31712
Y70
R
F
D
V
S
L
V
Y
L
T
R
K
F
M
D
Dog
Lupus familis
XP_852463
282
31896
Y70
R
F
D
V
S
L
V
Y
L
T
R
K
F
M
D
Cat
Felis silvestris
Mouse
Mus musculus
O54917
272
30864
Y70
R
F
D
V
S
L
V
Y
L
T
R
K
F
M
D
Rat
Rattus norvegicus
NP_001094187
272
30777
Y70
R
F
D
V
S
L
V
Y
L
T
R
K
F
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505549
547
60104
Y148
R
Y
D
V
S
L
V
Y
L
T
R
K
F
M
D
Chicken
Gallus gallus
Q90977
403
43534
L111
R
Y
E
T
S
L
N
L
T
T
K
R
F
L
E
Frog
Xenopus laevis
NP_001081986
429
46399
L149
R
Y
D
T
S
L
G
L
L
T
K
K
F
I
Q
Zebra Danio
Brachydanio rerio
NP_001025315
405
45233
Q189
R
S
E
V
A
L
G
Q
L
T
K
R
F
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
L138
R
Y
D
T
S
L
G
L
L
T
K
R
F
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
98.5
95
N.A.
83.9
85
N.A.
35.4
31.7
31.9
33
N.A.
N.A.
N.A.
N.A.
33.6
Protein Similarity:
100
88.2
98.9
96.8
N.A.
89.6
90
N.A.
43.5
47.3
46.1
46.9
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
33.3
53.3
46.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
73.3
73.3
73.3
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
73
10
0
0
0
0
0
0
0
0
0
0
64
% D
% Glu:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
55
0
0
0
0
0
0
0
0
0
0
91
0
0
% F
% Gly:
0
0
0
0
0
0
28
0
0
0
10
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
37
64
0
0
0
% K
% Leu:
0
0
0
0
10
91
0
28
82
0
0
0
0
19
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
64
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
19
% Q
% Arg:
91
0
0
0
0
0
10
0
0
0
55
28
0
0
0
% R
% Ser:
0
10
0
0
82
0
0
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
28
0
0
0
0
10
91
0
0
0
0
0
% T
% Val:
0
0
0
64
0
10
55
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
37
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _