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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRLF1
All Species:
22.73
Human Site:
Y173
Identified Species:
71.43
UniProt:
O75462
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75462
NP_004741.1
422
46302
Y173
H
T
N
Y
S
L
K
Y
K
L
R
W
Y
G
Q
Chimpanzee
Pan troglodytes
XP_001135263
705
76467
Y456
H
T
N
Y
S
L
K
Y
K
L
R
W
Y
G
Q
Rhesus Macaque
Macaca mulatta
XP_001115478
484
53005
Y235
H
T
N
Y
S
L
K
Y
K
L
R
W
Y
G
Q
Dog
Lupus familis
XP_541934
503
55315
Y254
H
T
N
Y
S
L
K
Y
K
L
R
W
Y
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM58
425
46643
Y176
H
T
N
Y
S
L
K
Y
K
L
R
W
Y
G
Q
Rat
Rattus norvegicus
NP_001099544
425
46556
Y176
H
T
N
Y
S
L
K
Y
K
L
R
W
Y
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509061
229
25903
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002650
389
43296
K148
G
E
T
F
I
K
T
K
Y
T
L
K
Y
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59
83.2
79.5
N.A.
94.5
94.1
N.A.
49.7
N.A.
N.A.
63
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.4
85.3
80.7
N.A.
95.7
95.5
N.A.
52.3
N.A.
N.A.
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% G
% His:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
13
75
13
75
0
0
13
0
13
0
% K
% Leu:
0
0
0
0
0
75
0
0
0
75
13
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% R
% Ser:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
75
13
0
0
0
13
0
0
13
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% W
% Tyr:
0
0
0
75
0
0
0
75
13
0
0
0
88
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _