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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGR5
All Species:
0
Human Site:
T20
Identified Species:
0
UniProt:
O75473
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75473
NP_003658.1
907
99998
T20
P
V
L
L
Q
L
A
T
G
G
S
S
P
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117502
907
99868
A20
P
V
L
L
Q
L
A
A
G
S
S
S
P
R
S
Dog
Lupus familis
XP_851831
728
79385
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1P4
907
99647
A20
L
A
L
L
Q
L
V
A
A
G
S
S
P
G
P
Rat
Rattus norvegicus
Q9Z2H4
951
104120
P21
G
L
L
G
S
A
G
P
S
G
A
A
P
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512452
917
101001
G32
W
I
F
L
P
V
L
G
C
C
R
F
P
K
A
Chicken
Gallus gallus
P79763
693
78680
Frog
Xenopus laevis
NP_001089881
955
105573
G20
S
L
L
V
C
C
S
G
G
P
S
G
V
S
S
Zebra Danio
Brachydanio rerio
XP_687184
961
103852
A20
L
C
V
G
G
Q
A
A
A
A
G
E
G
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476702
1360
150755
V79
Q
Q
L
S
Q
I
T
V
N
R
T
S
K
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
63.9
N.A.
85.7
47.7
N.A.
71.2
23.4
46.3
46.5
N.A.
24
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.5
69.7
N.A.
91.6
62.1
N.A.
81.2
42.1
60.9
61.5
N.A.
36.9
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
0
N.A.
53.3
20
N.A.
13.3
0
26.6
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
86.6
0
N.A.
53.3
40
N.A.
40
0
46.6
26.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
30
30
20
10
10
10
0
0
20
% A
% Cys:
0
10
0
0
10
10
0
0
10
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
0
20
10
0
10
20
30
30
10
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% K
% Leu:
20
20
60
40
0
30
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
20
0
0
0
10
0
0
10
0
10
0
0
50
10
10
% P
% Gln:
10
10
0
0
40
10
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
10
0
0
20
0
% R
% Ser:
10
0
0
10
10
0
10
0
10
10
40
40
0
20
40
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% T
% Val:
0
20
10
10
0
10
10
10
0
0
0
0
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _