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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERLIN1
All Species:
18.18
Human Site:
S291
Identified Species:
33.33
UniProt:
O75477
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75477
NP_001094096.1
346
38926
S291
K
K
Y
Q
A
I
A
S
N
S
K
I
Y
F
G
Chimpanzee
Pan troglodytes
XP_521583
346
38907
S291
K
K
Y
Q
A
I
A
S
N
S
K
I
Y
F
G
Rhesus Macaque
Macaca mulatta
XP_001107293
348
39167
S293
K
K
Y
Q
A
I
A
S
N
S
K
I
Y
F
G
Dog
Lupus familis
XP_851440
512
56230
S457
K
R
Y
Q
A
I
A
S
N
S
K
I
Y
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91X78
346
38918
S291
K
K
Y
Q
A
I
A
S
N
S
K
I
Y
F
G
Rat
Rattus norvegicus
B5DEH2
339
37692
K285
P
E
Y
L
Q
L
M
K
Y
K
A
I
A
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512971
328
36613
A272
K
K
Y
Q
A
I
A
A
N
S
K
I
Y
F
G
Chicken
Gallus gallus
NP_001026394
363
40801
A293
M
K
Y
Q
A
I
A
A
N
S
K
L
Y
F
G
Frog
Xenopus laevis
Q6DKC0
330
36828
L276
A
E
A
N
K
L
K
L
T
P
E
Y
L
Q
L
Zebra Danio
Brachydanio rerio
Q58EG2
342
38301
A288
L
Q
L
M
K
Y
Q
A
I
A
A
N
S
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623822
324
37202
A269
Y
Y
Q
T
K
M
Q
A
E
A
N
R
L
L
L
Nematode Worm
Caenorhab. elegans
NP_502339
312
35306
A258
S
E
R
S
K
A
D
A
E
F
Y
K
A
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141011
371
42459
A316
R
I
L
K
E
A
E
A
N
R
L
K
L
T
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
98.5
64.8
N.A.
95.9
72.5
N.A.
82
77.6
73.4
76.8
N.A.
N.A.
61.8
57.7
N.A.
Protein Similarity:
100
100
99.1
66.5
N.A.
97.9
81.5
N.A.
87.2
86.5
83.5
86.4
N.A.
N.A.
77.4
72.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
13.3
N.A.
93.3
80
0
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
93.3
20
20
N.A.
N.A.
20
13.3
N.A.
Percent
Protein Identity:
N.A.
49.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
66.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
54
16
54
47
0
16
16
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
24
0
0
8
0
8
0
16
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
54
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
54
0
0
8
0
0
54
0
0
8
% I
% Lys:
47
47
0
8
31
0
8
8
0
8
54
16
0
8
8
% K
% Leu:
8
0
16
8
0
16
0
8
0
0
8
8
24
8
16
% L
% Met:
8
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
62
0
8
8
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% P
% Gln:
0
8
8
54
8
0
16
0
0
0
0
0
0
16
0
% Q
% Arg:
8
8
8
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
8
0
0
8
0
0
0
39
0
54
0
0
8
8
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
62
0
0
8
0
0
8
0
8
8
54
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _