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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERLIN1
All Species:
19.39
Human Site:
S315
Identified Species:
35.56
UniProt:
O75477
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75477
NP_001094096.1
346
38926
S315
S
S
C
A
L
K
Y
S
D
I
R
T
G
R
E
Chimpanzee
Pan troglodytes
XP_521583
346
38907
S315
S
S
C
A
L
K
Y
S
D
I
R
T
G
R
E
Rhesus Macaque
Macaca mulatta
XP_001107293
348
39167
S317
S
S
C
A
L
K
Y
S
D
I
R
T
G
R
E
Dog
Lupus familis
XP_851440
512
56230
S481
S
S
C
A
S
K
Y
S
D
V
R
T
G
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91X78
346
38918
S315
S
S
C
A
L
K
Y
S
D
G
R
T
G
R
E
Rat
Rattus norvegicus
B5DEH2
339
37692
A309
P
N
M
F
M
D
S
A
G
G
L
G
K
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512971
328
36613
G296
S
C
P
L
K
A
A
G
G
N
A
R
T
V
R
Chicken
Gallus gallus
NP_001026394
363
40801
D317
S
C
A
F
Q
Q
A
D
L
R
T
T
Q
E
P
Frog
Xenopus laevis
Q6DKC0
330
36828
D300
S
K
I
Y
F
G
Q
D
I
P
N
M
F
M
D
Zebra Danio
Brachydanio rerio
Q58EG2
342
38301
R312
F
V
D
S
S
A
S
R
P
A
A
G
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623822
324
37202
T293
Y
E
A
L
A
Q
N
T
K
V
Y
Y
G
Q
D
Nematode Worm
Caenorhab. elegans
NP_502339
312
35306
Q282
T
K
E
Y
L
E
L
Q
K
I
R
A
I
A
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141011
371
42459
I340
S
I
A
N
N
S
K
I
F
F
G
E
K
I
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
98.5
64.8
N.A.
95.9
72.5
N.A.
82
77.6
73.4
76.8
N.A.
N.A.
61.8
57.7
N.A.
Protein Similarity:
100
100
99.1
66.5
N.A.
97.9
81.5
N.A.
87.2
86.5
83.5
86.4
N.A.
N.A.
77.4
72.5
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
0
N.A.
6.6
13.3
6.6
6.6
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
6.6
20
13.3
13.3
N.A.
N.A.
40
33.3
N.A.
Percent
Protein Identity:
N.A.
49.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
66.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
39
8
16
16
8
0
8
16
8
0
8
0
% A
% Cys:
0
16
39
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
16
39
0
0
0
0
0
16
% D
% Glu:
0
8
8
0
0
8
0
0
0
0
0
8
8
8
39
% E
% Phe:
8
0
0
16
8
0
0
0
8
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
8
0
8
16
16
8
16
47
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
8
8
31
0
0
8
8
0
% I
% Lys:
0
16
0
0
8
39
8
0
16
0
0
0
16
0
8
% K
% Leu:
0
0
0
16
39
0
8
0
8
0
8
0
0
0
0
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
8
0
8
8
0
8
0
0
8
8
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
8
8
0
0
0
0
16
% P
% Gln:
0
0
0
0
8
16
8
8
0
0
0
0
8
16
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
47
8
0
39
8
% R
% Ser:
70
39
0
8
16
8
16
39
0
0
0
0
0
8
16
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
8
47
8
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
16
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
16
0
0
39
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _