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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERLIN1
All Species:
18.18
Human Site:
Y268
Identified Species:
33.33
UniProt:
O75477
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75477
NP_001094096.1
346
38926
Y268
E
Y
Y
A
A
H
K
Y
A
T
S
N
K
H
K
Chimpanzee
Pan troglodytes
XP_521583
346
38907
Y268
E
Y
Y
A
A
H
K
Y
A
T
S
N
K
H
K
Rhesus Macaque
Macaca mulatta
XP_001107293
348
39167
Y270
E
Y
Y
A
A
H
K
Y
A
T
S
N
K
H
K
Dog
Lupus familis
XP_851440
512
56230
Y434
E
Y
Y
A
A
H
K
Y
A
T
S
N
K
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91X78
346
38918
Y268
E
Y
Y
A
A
H
K
Y
A
T
S
N
K
H
K
Rat
Rattus norvegicus
B5DEH2
339
37692
C262
K
A
K
A
D
A
E
C
Y
T
A
L
K
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512971
328
36613
H249
E
F
Y
T
A
Y
K
H
A
T
S
N
K
L
K
Chicken
Gallus gallus
NP_001026394
363
40801
L270
D
Y
Y
T
A
Q
K
L
A
D
S
N
K
L
K
Frog
Xenopus laevis
Q6DKC0
330
36828
R253
E
D
F
A
F
L
A
R
E
K
A
R
A
D
A
Zebra Danio
Brachydanio rerio
Q58EG2
342
38301
A265
A
D
A
E
Y
Y
T
A
A
K
F
A
E
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623822
324
37202
E246
L
Q
R
I
A
T
I
E
D
E
M
H
L
A
R
Nematode Worm
Caenorhab. elegans
NP_502339
312
35306
E235
K
R
L
L
S
E
K
E
T
E
K
L
L
N
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141011
371
42459
D293
R
Q
E
Q
I
D
N
D
M
Y
L
A
R
E
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
98.5
64.8
N.A.
95.9
72.5
N.A.
82
77.6
73.4
76.8
N.A.
N.A.
61.8
57.7
N.A.
Protein Similarity:
100
100
99.1
66.5
N.A.
97.9
81.5
N.A.
87.2
86.5
83.5
86.4
N.A.
N.A.
77.4
72.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
66.6
60
13.3
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
86.6
66.6
26.6
20
N.A.
N.A.
20
33.3
N.A.
Percent
Protein Identity:
N.A.
49.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
66.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
54
62
8
8
8
62
0
16
16
8
16
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
0
8
8
0
8
8
8
0
0
0
8
0
% D
% Glu:
54
0
8
8
0
8
8
16
8
16
0
0
8
8
0
% E
% Phe:
0
8
8
0
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
39
0
8
0
0
0
8
0
39
0
% H
% Ile:
0
0
0
8
8
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
16
0
8
0
0
0
62
0
0
16
8
0
62
0
62
% K
% Leu:
8
0
8
8
0
8
0
8
0
0
8
16
16
16
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
54
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
8
0
8
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
8
8
0
0
0
0
8
0
0
0
8
8
0
8
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
54
0
0
0
0
% S
% Thr:
0
0
0
16
0
8
8
0
8
54
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
47
54
0
8
16
0
39
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _