KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC4
All Species:
22.42
Human Site:
T375
Identified Species:
54.81
UniProt:
O75487
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75487
NP_001439.2
556
62412
T375
H
H
P
E
E
R
P
T
T
A
A
G
T
S
L
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
F398
L
I
Q
K
L
K
S
F
I
S
F
Y
S
A
L
Rhesus Macaque
Macaca mulatta
XP_001097252
556
62451
T375
H
H
P
E
E
R
P
T
T
A
A
G
T
S
L
Dog
Lupus familis
XP_549265
556
62414
T375
Y
H
P
E
E
R
P
T
T
A
A
G
T
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P51655
557
62568
T375
Y
H
P
E
Q
R
P
T
T
A
A
G
T
S
L
Rat
Rattus norvegicus
P35053
558
61716
E368
R
A
K
L
A
L
Q
E
K
S
S
T
G
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514704
559
62784
T375
Y
N
P
E
E
R
P
T
T
A
A
G
T
S
L
Chicken
Gallus gallus
P50593
550
61065
L372
A
K
S
S
A
V
A
L
E
M
L
V
L
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103189
562
63478
T374
N
S
P
E
E
R
P
T
T
A
A
G
T
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
N429
R
P
P
P
H
K
N
N
V
K
W
A
T
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.6
99
94.4
N.A.
94.6
44.2
N.A.
82.6
46.9
N.A.
55.1
N.A.
24.2
N.A.
N.A.
N.A.
Protein Similarity:
100
45.8
99.2
96.5
N.A.
96.4
64.3
N.A.
89.2
66.9
N.A.
73.3
N.A.
43.2
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
6.6
N.A.
86.6
0
N.A.
86.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
26.6
N.A.
100
0
N.A.
93.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
20
0
10
0
0
60
60
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% D
% Glu:
0
0
0
60
50
0
0
10
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
60
10
0
0
% G
% His:
20
40
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
10
10
0
20
0
0
10
10
0
0
0
0
0
% K
% Leu:
10
0
0
10
10
10
0
10
0
0
10
0
10
0
80
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
10
70
10
0
0
60
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
10
0
10
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
10
0
0
10
0
0
20
10
0
10
60
0
% S
% Thr:
0
0
0
0
0
0
0
60
60
0
0
10
70
10
0
% T
% Val:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
30
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _