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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPC4 All Species: 22.73
Human Site: Y193 Identified Species: 55.56
UniProt: O75487 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75487 NP_001439.2 556 62412 Y193 Y L E C V S K Y T E Q L K P F
Chimpanzee Pan troglodytes A5A6P7 580 65546 A201 I N E C L R G A R R D L K V F
Rhesus Macaque Macaca mulatta XP_001097252 556 62451 Y193 Y L E C V S K Y T E Q L K P F
Dog Lupus familis XP_549265 556 62414 Y193 Y L E C V S K Y T E Q L K P F
Cat Felis silvestris
Mouse Mus musculus P51655 557 62568 Y193 Y L E C V S K Y T E Q L K P F
Rat Rattus norvegicus P35053 558 61716 Q195 Y L D C L G K Q A E A L R P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514704 559 62784 Y193 Y L E C V S K Y T E Q L K P F
Chicken Gallus gallus P50593 550 61065 H192 Y L D C M V K H A E Q H K P F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103189 562 63478 Y192 Y L E C I S K Y T D Q L K P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24114 626 69013 N248 Y V N C L Q H N F D E M H P F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.6 99 94.4 N.A. 94.6 44.2 N.A. 82.6 46.9 N.A. 55.1 N.A. 24.2 N.A. N.A. N.A.
Protein Similarity: 100 45.8 99.2 96.5 N.A. 96.4 64.3 N.A. 89.2 66.9 N.A. 73.3 N.A. 43.2 N.A. N.A. N.A.
P-Site Identity: 100 33.3 100 100 N.A. 100 53.3 N.A. 100 60 N.A. 86.6 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 73.3 N.A. 100 80 N.A. 100 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 20 0 10 0 0 0 0 % A
% Cys: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 0 0 0 0 0 20 10 0 0 0 0 % D
% Glu: 0 0 70 0 0 0 0 0 0 70 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 100 % F
% Gly: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 10 0 0 0 10 10 0 0 % H
% Ile: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 80 0 0 0 0 0 80 0 0 % K
% Leu: 0 80 0 0 30 0 0 0 0 0 0 80 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 10 10 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 % P
% Gln: 0 0 0 0 0 10 0 10 0 0 70 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 10 10 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 % T
% Val: 0 10 0 0 50 10 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 90 0 0 0 0 0 0 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _