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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA11
All Species:
14.85
Human Site:
S199
Identified Species:
29.7
UniProt:
O75493
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75493
NP_001208.2
328
36238
S199
S
T
S
N
P
F
L
S
R
L
L
N
R
D
T
Chimpanzee
Pan troglodytes
Q7M317
261
28893
K150
A
V
I
G
V
L
M
K
V
G
E
A
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001113730
466
51836
S199
G
S
S
N
P
F
L
S
R
L
L
N
R
D
T
Dog
Lupus familis
XP_852031
328
36084
S199
G
S
S
N
P
F
L
S
R
L
L
N
R
D
T
Cat
Felis silvestris
Mouse
Mus musculus
O70354
328
36032
S199
G
S
S
N
P
F
L
S
R
L
L
N
R
D
T
Rat
Rattus norvegicus
P43165
304
34481
A191
K
L
G
A
H
H
E
A
L
Q
R
L
V
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507020
305
34813
T183
M
L
N
R
D
T
I
T
R
I
T
Y
K
N
D
Chicken
Gallus gallus
P07630
260
28989
K148
A
V
V
G
I
F
M
K
V
G
N
A
K
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q92051
260
28659
K148
A
V
V
G
V
F
L
K
I
G
A
A
N
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572581
327
37164
E193
L
G
D
L
S
N
A
E
L
R
M
L
T
D
Q
Honey Bee
Apis mellifera
XP_396828
317
36266
R190
D
L
S
N
P
E
L
R
I
F
T
E
Q
L
D
Nematode Worm
Caenorhab. elegans
Q18932
337
37612
V220
F
P
G
C
H
E
T
V
T
W
V
I
L
N
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.9
68
98.4
N.A.
96.9
29.2
N.A.
50
26.2
N.A.
25.9
N.A.
36.5
36.5
32.3
N.A.
Protein Similarity:
100
42.3
68.6
98.7
N.A.
98.1
45.4
N.A.
66.4
43.5
N.A.
41.4
N.A.
53.6
52.7
52.8
N.A.
P-Site Identity:
100
0
86.6
86.6
N.A.
86.6
6.6
N.A.
6.6
6.6
N.A.
13.3
N.A.
6.6
26.6
0
N.A.
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
93.3
13.3
N.A.
46.6
26.6
N.A.
20
N.A.
13.3
33.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
9
0
0
9
9
0
0
9
25
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
9
0
0
0
0
0
0
0
0
50
17
% D
% Glu:
0
0
0
0
0
17
9
9
0
0
9
9
0
0
9
% E
% Phe:
9
0
0
0
0
50
0
0
0
9
0
0
0
0
0
% F
% Gly:
25
9
17
25
0
0
0
0
0
25
0
0
0
0
0
% G
% His:
0
0
0
0
17
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
9
0
9
0
17
9
0
9
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
25
0
0
0
0
17
0
9
% K
% Leu:
9
25
0
9
0
9
50
0
17
34
34
17
9
9
0
% L
% Met:
9
0
0
0
0
0
17
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
42
0
9
0
0
0
0
9
34
17
17
9
% N
% Pro:
0
9
0
0
42
0
0
0
0
0
0
0
0
25
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
9
% Q
% Arg:
0
0
0
9
0
0
0
9
42
9
9
0
34
0
9
% R
% Ser:
9
25
42
0
9
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
9
9
9
9
0
17
0
9
0
34
% T
% Val:
0
25
17
0
17
0
0
9
17
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _