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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS13A All Species: 4.55
Human Site: S141 Identified Species: 9.09
UniProt: O75494 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75494 NP_006616.1 262 31301 S141 F D Y N Y R R S Y S P R N S R
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S101 R P P D S H H S R R G P P P R
Rhesus Macaque Macaca mulatta XP_001093719 261 31195 R140 S F D Y N Y R R S Y S P R N R
Dog Lupus familis XP_547294 217 25660 D97 V Q F E D V R D A E D A L H N
Cat Felis silvestris
Mouse Mus musculus Q62093 221 25458 S101 R P P D S H H S R R G P P P R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P30352 221 25506 S101 R P P D S H H S R R G P P P R
Frog Xenopus laevis NP_001079656 258 30267 N137 R S R S I E Q N Y G R S N S P
Zebra Danio Brachydanio rerio Q7SXP4 257 28365 S128 Y G P P S R R S E Y R V I V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02427 144 15994 K24 N L G S S A S K H E I E G A F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09511 196 22569 A76 E R R D A E H A L D R T D G K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151991 209 24579 P88 G F V Q Y Y D P A D A A D A K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 Y163 G T T G V V D Y T C Y E D M K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.6 99.6 62.5 N.A. 37 N.A. N.A. N.A. 37.4 75.1 24.8 N.A. 24.4 N.A. 35.1 N.A.
Protein Similarity: 100 50.7 99.6 66 N.A. 51.5 N.A. N.A. N.A. 51.5 82.8 37.7 N.A. 35.5 N.A. 48.8 N.A.
P-Site Identity: 100 13.3 13.3 6.6 N.A. 13.3 N.A. N.A. N.A. 13.3 20 20 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 20 20 13.3 N.A. 20 N.A. N.A. N.A. 20 40 26.6 N.A. 20 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. 22.5 N.A. 30.3 N.A. N.A.
Protein Similarity: N.A. 34.7 N.A. 47.5 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 9 0 9 17 0 9 17 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 9 9 34 9 0 17 9 0 17 9 0 25 0 0 % D
% Glu: 9 0 0 9 0 17 0 0 9 17 0 17 0 0 0 % E
% Phe: 9 17 9 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 17 9 9 9 0 0 0 0 0 9 25 0 9 9 0 % G
% His: 0 0 0 0 0 25 34 0 9 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 9 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 25 % K
% Leu: 0 9 0 0 0 0 0 0 9 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 9 0 0 9 9 0 0 9 0 0 0 0 17 9 9 % N
% Pro: 0 25 34 9 0 0 0 9 0 0 9 34 25 25 9 % P
% Gln: 0 9 0 9 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 34 9 17 0 0 17 34 9 25 25 25 9 9 0 42 % R
% Ser: 9 9 0 17 42 0 9 42 9 9 9 9 0 17 9 % S
% Thr: 0 9 9 0 0 0 0 0 9 0 0 9 0 0 0 % T
% Val: 9 0 9 0 9 17 0 0 0 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 9 9 17 17 0 9 17 17 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _