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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS13A All Species: 13.03
Human Site: S185 Identified Species: 26.06
UniProt: O75494 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75494 NP_006616.1 262 31301 S185 N S R S R S K S Q P K K E M K
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S145 S R S R S R Y S R S K S R S R
Rhesus Macaque Macaca mulatta XP_001093719 261 31195 S184 N S R S R S K S Q P K K E M K
Dog Lupus familis XP_547294 217 25660 S141 E G R N V Y S S S R Y D D Y D
Cat Felis silvestris
Mouse Mus musculus Q62093 221 25458 S145 S R S R S R Y S R S K S R S R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P30352 221 25506 S145 S R S R S R Y S R S K S R S R
Frog Xenopus laevis NP_001079656 258 30267 S181 R S G S N S R S R S K S E P K
Zebra Danio Brachydanio rerio Q7SXP4 257 28365 V172 G T G V V E F V R K E D M T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02427 144 15994 D68 E D A T R A L D G T R C C G T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09511 196 22569 R120 R R R S R S P R R R S R S P R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151991 209 24579 H132 A R D R V R G H S Y D D R R Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 G207 D S R S P S R G R S Y S K S R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.6 99.6 62.5 N.A. 37 N.A. N.A. N.A. 37.4 75.1 24.8 N.A. 24.4 N.A. 35.1 N.A.
Protein Similarity: 100 50.7 99.6 66 N.A. 51.5 N.A. N.A. N.A. 51.5 82.8 37.7 N.A. 35.5 N.A. 48.8 N.A.
P-Site Identity: 100 13.3 100 13.3 N.A. 13.3 N.A. N.A. N.A. 13.3 46.6 0 N.A. 6.6 N.A. 26.6 N.A.
P-Site Similarity: 100 33.3 100 26.6 N.A. 33.3 N.A. N.A. N.A. 33.3 60 20 N.A. 26.6 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. 22.5 N.A. 30.3 N.A. N.A.
Protein Similarity: N.A. 34.7 N.A. 47.5 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. 0 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % C
% Asp: 9 9 9 0 0 0 0 9 0 0 9 25 9 0 9 % D
% Glu: 17 0 0 0 0 9 0 0 0 0 9 0 25 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 17 0 0 0 9 9 9 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 17 0 0 9 50 17 9 0 25 % K
% Leu: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 17 0 % M
% Asn: 17 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 9 0 0 17 0 0 0 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Q
% Arg: 17 42 42 34 34 34 17 9 59 17 9 9 34 9 42 % R
% Ser: 25 34 25 42 25 42 9 59 17 42 9 42 9 34 0 % S
% Thr: 0 9 0 9 0 0 0 0 0 9 0 0 0 9 9 % T
% Val: 0 0 0 9 25 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 25 0 0 9 17 0 0 9 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _