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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMNN
All Species:
15.45
Human Site:
S189
Identified Species:
34
UniProt:
O75496
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75496
NP_056979.1
209
23565
S189
E
D
S
L
V
E
D
S
E
I
G
T
C
A
E
Chimpanzee
Pan troglodytes
XP_001171862
209
23550
S189
E
D
S
L
V
E
D
S
E
I
G
T
C
A
E
Rhesus Macaque
Macaca mulatta
XP_001101599
209
23555
S189
E
D
S
V
G
E
D
S
E
I
G
T
C
A
E
Dog
Lupus familis
XP_535906
427
46469
P407
E
G
S
D
V
E
D
P
D
V
G
M
C
A
E
Cat
Felis silvestris
Mouse
Mus musculus
O88513
206
23281
S186
E
Y
S
E
L
E
D
S
G
A
G
T
C
A
E
Rat
Rattus norvegicus
NP_001099582
206
23103
S186
E
Y
S
E
P
E
D
S
D
T
G
T
C
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513504
199
22131
E179
A
G
G
D
P
E
G
E
D
A
D
T
P
G
E
Chicken
Gallus gallus
NP_001026181
187
21298
E168
I
E
R
L
T
G
Q
E
S
D
N
L
E
A
L
Frog
Xenopus laevis
NP_001084216
219
25357
A194
F
E
D
E
A
D
M
A
E
A
R
I
E
D
E
Zebra Danio
Brachydanio rerio
NP_956380
241
27338
Q209
E
E
H
E
D
E
D
Q
E
H
D
C
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789704
254
28148
E232
D
E
V
F
V
H
K
E
D
I
E
D
D
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.7
37.7
N.A.
77.5
75.1
N.A.
56.4
49.2
48.4
41
N.A.
N.A.
N.A.
N.A.
25.9
Protein Similarity:
100
99
97.1
41.6
N.A.
86.5
85.1
N.A.
67.9
63.1
64.3
56.8
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
100
86.6
60
N.A.
66.6
66.6
N.A.
20
13.3
13.3
33.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
73.3
N.A.
73.3
73.3
N.A.
26.6
20
33.3
40
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
10
0
28
0
0
0
73
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
55
0
0
% C
% Asp:
10
28
10
19
10
10
64
0
37
10
19
10
10
10
0
% D
% Glu:
64
37
0
37
0
73
0
28
46
0
10
0
28
0
82
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
10
0
10
10
10
0
10
0
55
0
0
19
0
% G
% His:
0
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
37
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
28
10
0
0
0
0
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
19
0
0
10
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
55
0
0
0
0
46
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
10
0
55
0
0
0
% T
% Val:
0
0
10
10
37
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _