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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLN5
All Species:
6.67
Human Site:
S49
Identified Species:
24.44
UniProt:
O75503
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75503
NP_006484.1
358
41497
S49
S
R
V
S
G
I
P
S
R
R
H
W
P
V
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086029
378
43178
S69
P
R
A
S
G
V
L
S
R
R
H
W
P
V
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMW8
341
39311
S44
P
V
P
Y
K
R
F
S
F
R
P
K
T
D
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512593
584
66848
I275
V
T
S
P
L
R
V
I
P
G
K
F
P
V
L
Chicken
Gallus gallus
XP_417005
339
39260
T60
A
R
Y
T
F
C
P
T
G
S
A
I
P
V
M
Frog
Xenopus laevis
NP_001121215
114
13307
Zebra Danio
Brachydanio rerio
XP_697882
329
38435
P45
D
K
R
P
D
V
D
P
F
C
Q
A
L
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
89.6
N.A.
N.A.
72.6
N.A.
N.A.
48.1
69.8
20.1
52.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
92.5
N.A.
N.A.
82.4
N.A.
N.A.
54.4
79
24
67.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
73.3
N.A.
N.A.
20
N.A.
N.A.
13.3
26.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
80
N.A.
N.A.
20
N.A.
N.A.
20
46.6
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
0
0
0
0
0
0
0
15
15
0
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
15
0
0
0
0
0
% C
% Asp:
15
0
0
0
15
0
15
0
0
0
0
0
0
15
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
15
0
15
0
29
0
0
15
0
0
0
% F
% Gly:
0
0
0
0
29
0
0
0
15
15
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
15
0
0
0
15
0
0
0
% I
% Lys:
0
15
0
0
15
0
0
0
0
0
15
15
0
0
0
% K
% Leu:
0
0
0
0
15
0
15
0
0
0
0
0
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
29
0
15
29
0
0
29
15
15
0
15
0
58
0
58
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% Q
% Arg:
0
43
15
0
0
29
0
0
29
43
0
0
0
0
0
% R
% Ser:
15
0
15
29
0
0
0
43
0
15
0
0
0
0
0
% S
% Thr:
0
15
0
15
0
0
0
15
0
0
0
0
15
0
0
% T
% Val:
15
15
15
0
0
29
15
0
0
0
0
0
0
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
29
0
0
0
% W
% Tyr:
0
0
15
15
0
0
0
0
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _