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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN11
All Species:
27.27
Human Site:
S49
Identified Species:
66.67
UniProt:
O75508
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75508
NP_005593.2
207
21993
S49
R
K
L
D
E
L
G
S
K
G
L
W
A
D
C
Chimpanzee
Pan troglodytes
XP_516873
207
22019
S49
R
K
L
D
E
L
G
S
K
G
L
W
A
D
C
Rhesus Macaque
Macaca mulatta
XP_001089174
207
21927
S49
R
K
L
D
E
L
G
S
K
G
L
W
A
D
C
Dog
Lupus familis
XP_545284
430
44247
S272
R
K
L
D
E
L
G
S
K
G
L
W
A
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q60771
207
22096
S49
R
K
M
D
E
L
G
S
K
G
L
W
A
D
C
Rat
Rattus norvegicus
Q99P82
207
22028
S49
R
K
M
D
E
L
G
S
K
G
L
W
A
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521064
76
7978
Chicken
Gallus gallus
XP_422797
207
22085
S49
R
K
M
D
E
L
G
S
K
G
L
W
A
D
C
Frog
Xenopus laevis
NP_001088886
221
23846
G49
T
A
V
G
L
Y
E
G
L
W
M
S
C
A
S
Zebra Danio
Brachydanio rerio
NP_001002624
215
23224
A49
R
K
M
D
E
L
E
A
K
G
L
W
A
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
46.5
N.A.
94.1
92.7
N.A.
33.3
85
28.9
56.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99
47.9
N.A.
98.5
97.5
N.A.
34.7
92.7
45.2
74.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
93.3
0
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
13.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
0
0
0
80
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
80
% C
% Asp:
0
0
0
80
0
0
0
0
0
0
0
0
0
80
0
% D
% Glu:
0
0
0
0
80
0
20
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
70
10
0
80
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
80
0
0
0
0
0
0
80
0
0
0
0
0
0
% K
% Leu:
0
0
40
0
10
80
0
0
10
0
80
0
0
0
0
% L
% Met:
0
0
40
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
70
0
0
0
10
0
0
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
80
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _