Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLDN11 All Species: 26.67
Human Site: Y117 Identified Species: 65.19
UniProt: O75508 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75508 NP_005593.2 207 21993 Y117 Q E P G V A K Y R R A Q L A G
Chimpanzee Pan troglodytes XP_516873 207 22019 Y117 Q E P G V A K Y R R A Q L A G
Rhesus Macaque Macaca mulatta XP_001089174 207 21927 Y117 H E P G V A K Y R R A Q L A G
Dog Lupus familis XP_545284 430 44247 Y340 H E P G V A K Y R R A Q L A G
Cat Felis silvestris
Mouse Mus musculus Q60771 207 22096 Y117 H E P G V A K Y R R A Q L A G
Rat Rattus norvegicus Q99P82 207 22028 Y117 H E P G V A K Y R R A Q L A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521064 76 7978 F10 A I V A T I W F P V C A H R E
Chicken Gallus gallus XP_422797 207 22085 Y117 H E P G A A K Y R R S Q L G G
Frog Xenopus laevis NP_001088886 221 23846 S116 D N N P I T K S R I A V S G G
Zebra Danio Brachydanio rerio NP_001002624 215 23224 N117 G E P E S A K N K R S V L G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.5 46.5 N.A. 94.1 92.7 N.A. 33.3 85 28.9 56.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 99 47.9 N.A. 98.5 97.5 N.A. 34.7 92.7 45.2 74.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 0 73.3 26.6 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 6.6 80 33.3 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 10 80 0 0 0 0 70 10 0 60 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 80 0 10 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 70 0 0 0 0 0 0 0 0 0 30 90 % G
% His: 50 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 10 0 0 10 10 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 90 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 80 10 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 20 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 80 80 0 0 0 10 0 % R
% Ser: 0 0 0 0 10 0 0 10 0 0 20 0 10 0 0 % S
% Thr: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 60 0 0 0 0 10 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _