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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PECI All Species: 19.39
Human Site: S116 Identified Species: 38.79
UniProt: O75521 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75521 NP_006108.2 394 43585 S116 Q N Y V D L V S S L S P S L E
Chimpanzee Pan troglodytes XP_527221 392 43322 S114 Q N Y V D L V S S L S P S L E
Rhesus Macaque Macaca mulatta XP_001094776 392 43283 S114 Q N Y V D L V S S L S S S L E
Dog Lupus familis XP_535873 659 72908 V381 R Q N Y V D L V S D L S S S D
Cat Felis silvestris
Mouse Mus musculus Q9WUR2 391 43249 S114 Q N Y V D L V S S L S S S S E
Rat Rattus norvegicus Q5XIC0 391 43003 S114 Q N Y V D L V S S L S S S S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508493 358 39782 Q102 P S G G E H Q Q Y E T L R V T
Chicken Gallus gallus XP_001231829 401 44396 S123 E Y T K L V S S L I S A E S A
Frog Xenopus laevis NP_001089808 358 40132 H100 N T E P S I G H K M Y E T I Q
Zebra Danio Brachydanio rerio NP_001002645 357 39080 T101 Q P T G G G K T F Q T L L V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41942 255 28088 P22 L W V T L N R P K K F N A L T
Sea Urchin Strong. purpuratus XP_780031 398 43708 D121 E K Y V G I V D D L V A Q E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 92.8 47.9 N.A. 73 74.1 N.A. 65.9 65 59.1 58.8 N.A. N.A. N.A. 27.1 51.7
Protein Similarity: 100 98.7 96.4 53.2 N.A. 83.5 84 N.A. 76.6 76.8 71.8 71.5 N.A. N.A. N.A. 43.4 66.8
P-Site Identity: 100 100 93.3 13.3 N.A. 86.6 86.6 N.A. 0 13.3 0 6.6 N.A. N.A. N.A. 6.6 26.6
P-Site Similarity: 100 100 93.3 33.3 N.A. 86.6 86.6 N.A. 26.6 33.3 33.3 26.6 N.A. N.A. N.A. 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 17 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 42 9 0 9 9 9 0 0 0 0 9 % D
% Glu: 17 0 9 0 9 0 0 0 0 9 0 9 9 9 42 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % F
% Gly: 0 0 9 17 17 9 9 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 17 0 0 0 9 0 0 0 9 0 % I
% Lys: 0 9 0 9 0 0 9 0 17 9 0 0 0 0 0 % K
% Leu: 9 0 0 0 17 42 9 0 9 50 9 17 9 34 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 9 42 9 0 0 9 0 0 0 0 0 9 0 0 0 % N
% Pro: 9 9 0 9 0 0 0 9 0 0 0 17 0 0 0 % P
% Gln: 50 9 0 0 0 0 9 9 0 9 0 0 9 0 9 % Q
% Arg: 9 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % R
% Ser: 0 9 0 0 9 0 9 50 50 0 50 34 50 34 9 % S
% Thr: 0 9 17 9 0 0 0 9 0 0 17 0 9 0 17 % T
% Val: 0 0 9 50 9 9 50 9 0 0 9 0 0 17 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 50 9 0 0 0 0 9 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _