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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PECI
All Species:
16.36
Human Site:
S125
Identified Species:
32.73
UniProt:
O75521
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75521
NP_006108.2
394
43585
S125
L
S
P
S
L
E
S
S
S
Q
V
E
P
G
T
Chimpanzee
Pan troglodytes
XP_527221
392
43322
S123
L
S
P
S
L
E
S
S
S
Q
V
E
P
G
T
Rhesus Macaque
Macaca mulatta
XP_001094776
392
43283
S123
L
S
S
S
L
E
S
S
S
Q
V
E
P
G
T
Dog
Lupus familis
XP_535873
659
72908
S390
D
L
S
S
S
D
S
S
S
Q
V
K
P
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUR2
391
43249
P123
L
S
S
S
S
E
A
P
S
Q
G
K
R
G
A
Rat
Rattus norvegicus
Q5XIC0
391
43003
S123
L
S
S
S
S
E
A
S
S
Q
G
K
G
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508493
358
39782
E111
E
T
L
R
V
T
T
E
N
N
I
T
K
I
I
Chicken
Gallus gallus
XP_001231829
401
44396
Q132
I
S
A
E
S
A
G
Q
K
K
D
T
S
P
G
Frog
Xenopus laevis
NP_001089808
358
40132
S109
M
Y
E
T
I
Q
V
S
C
E
D
R
I
T
K
Zebra Danio
Brachydanio rerio
NP_001002645
357
39080
E110
Q
T
L
L
V
S
T
E
D
N
I
T
T
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41942
255
28088
Q31
K
F
N
A
L
T
R
Q
M
F
L
D
L
C
T
Sea Urchin
Strong. purpuratus
XP_780031
398
43708
E130
L
V
A
Q
E
G
G
E
A
E
T
A
S
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
92.8
47.9
N.A.
73
74.1
N.A.
65.9
65
59.1
58.8
N.A.
N.A.
N.A.
27.1
51.7
Protein Similarity:
100
98.7
96.4
53.2
N.A.
83.5
84
N.A.
76.6
76.8
71.8
71.5
N.A.
N.A.
N.A.
43.4
66.8
P-Site Identity:
100
100
93.3
46.6
N.A.
46.6
53.3
N.A.
0
6.6
6.6
0
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
93.3
60
N.A.
60
66.6
N.A.
33.3
20
40
26.6
N.A.
N.A.
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
0
9
17
0
9
0
0
9
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% C
% Asp:
9
0
0
0
0
9
0
0
9
0
17
9
0
0
0
% D
% Glu:
9
0
9
9
9
42
0
25
0
17
0
25
0
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
17
0
0
0
17
0
9
42
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
17
0
9
17
9
% I
% Lys:
9
0
0
0
0
0
0
0
9
9
0
25
9
0
9
% K
% Leu:
50
9
17
9
34
0
0
0
0
0
9
0
9
0
0
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
9
17
0
0
0
0
0
% N
% Pro:
0
0
17
0
0
0
0
9
0
0
0
0
34
9
0
% P
% Gln:
9
0
0
9
0
9
0
17
0
50
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
9
0
0
0
0
9
9
0
9
% R
% Ser:
0
50
34
50
34
9
34
50
50
0
0
0
17
0
0
% S
% Thr:
0
17
0
9
0
17
17
0
0
0
9
25
9
17
42
% T
% Val:
0
9
0
0
17
0
9
0
0
0
34
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _