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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBMXL2 All Species: 10
Human Site: S222 Identified Species: 20
UniProt: O75526 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75526 NP_055284.3 392 42814 S222 S S R D G Y S S R D Y R E P R
Chimpanzee Pan troglodytes P0C8Z4 992 107523 F822 Y S R G R N S F S N S Y G Q S
Rhesus Macaque Macaca mulatta XP_001102988 415 45763 L243 G P L L R E P L P R C R D P G
Dog Lupus familis XP_853786 588 64470 S341 S T K D S Y S S R D Y P S S R
Cat Felis silvestris
Mouse Mus musculus O35479 388 42215 S218 Y S T K D S Y S S R D Y P S S
Rat Rattus norvegicus P84586 388 42185 S219 S T K D S Y S S R D Y P S S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510789 394 42453 Y226 D S Y S S R D Y P S S R D T R
Chicken Gallus gallus NP_001073196 385 41433 T219 D Y P S S R D T R D Y A P P P
Frog Xenopus laevis O93235 166 17885
Zebra Danio Brachydanio rerio NP_997763 379 41603 D212 R D Y M S S R D S R D Y G P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P10979 157 15420
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q03250 176 16871 G14 E Y R C F V G G L A W A T D D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.8 64.8 40.6 N.A. 70.9 71.1 N.A. 72.3 71.4 29.3 61.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 33.1 71 48.4 N.A. 77 77.5 N.A. 79.4 77.3 34.4 68.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 13.3 60 N.A. 13.3 60 N.A. 20 26.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 20 73.3 N.A. 13.3 73.3 N.A. 26.6 33.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 26.7 N.A. 28 N.A. N.A.
Protein Similarity: N.A. 30.1 N.A. 32.6 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 0 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 17 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 17 9 0 25 9 0 17 9 0 34 17 0 17 9 9 % D
% Glu: 9 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 9 0 9 9 0 0 0 0 17 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 17 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 9 0 0 0 9 9 0 0 0 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 9 9 0 0 0 9 0 17 0 0 17 17 34 17 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 9 0 25 0 17 17 9 0 34 25 0 25 0 0 34 % R
% Ser: 25 34 0 17 42 17 34 34 25 9 17 0 17 25 17 % S
% Thr: 0 17 9 0 0 0 0 9 0 0 0 0 9 9 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 17 17 17 0 0 25 9 9 0 0 34 25 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _