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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TADA3
All Species:
37.88
Human Site:
S275
Identified Species:
69.44
UniProt:
O75528
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75528
NP_006345.1
432
48902
S275
L
V
E
E
N
I
I
S
P
M
E
D
S
P
I
Chimpanzee
Pan troglodytes
XP_001147226
432
48912
S275
L
V
E
E
N
I
I
S
P
M
E
D
S
P
I
Rhesus Macaque
Macaca mulatta
XP_001094396
370
41842
G227
D
K
K
K
G
L
M
G
P
L
T
E
L
D
T
Dog
Lupus familis
XP_861667
413
46605
S256
L
V
E
E
N
I
I
S
P
M
E
D
S
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0L9
432
48882
S275
L
V
E
E
N
I
I
S
P
M
E
D
S
P
I
Rat
Rattus norvegicus
Q4V8F5
432
48880
S275
L
V
E
E
N
I
I
S
P
M
E
D
S
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507206
432
48899
S275
L
V
E
E
N
I
I
S
P
I
E
D
S
P
I
Chicken
Gallus gallus
XP_414389
432
48755
S275
L
V
E
E
N
I
I
S
P
V
E
D
S
P
I
Frog
Xenopus laevis
Q6PGT0
432
49041
S275
L
V
E
E
N
I
I
S
P
V
E
D
S
P
I
Zebra Danio
Brachydanio rerio
Q7SY21
429
48890
S273
L
V
E
E
N
I
I
S
P
M
E
D
S
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523395
556
59898
T379
V
G
E
H
S
N
S
T
T
S
S
S
N
E
N
Honey Bee
Apis mellifera
XP_395126
461
52200
V297
L
L
E
E
N
V
Y
V
A
N
N
N
T
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799180
450
51306
E292
E
N
I
M
C
P
L
E
E
E
F
L
M
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
85.6
95.5
N.A.
99.3
98.6
N.A.
95.8
92.8
87.2
78.4
N.A.
26.6
36
N.A.
55.3
Protein Similarity:
100
100
85.6
95.5
N.A.
99.7
99.3
N.A.
98.6
96.7
95.1
90.2
N.A.
42.2
56.8
N.A.
74.2
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
93.3
93.3
93.3
100
N.A.
6.6
26.6
N.A.
0
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
33.3
53.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
70
0
24
0
% D
% Glu:
8
0
85
77
0
0
0
8
8
8
70
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
70
70
0
0
8
0
0
0
0
70
% I
% Lys:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
77
8
0
0
0
8
8
0
0
8
0
8
8
0
0
% L
% Met:
0
0
0
8
0
0
8
0
0
47
0
0
8
0
0
% M
% Asn:
0
8
0
0
77
8
0
0
0
8
8
8
8
0
16
% N
% Pro:
0
0
0
0
0
8
0
0
77
0
0
0
0
70
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
8
70
0
8
8
8
70
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
8
0
8
0
8
% T
% Val:
8
70
0
0
0
8
0
8
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _