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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAF5L
All Species:
14.55
Human Site:
Y395
Identified Species:
29.09
UniProt:
O75529
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75529
NP_001020418.1
589
66155
Y395
W
D
L
D
I
S
P
Y
S
L
Y
F
A
S
G
Chimpanzee
Pan troglodytes
XP_001135279
800
86826
Y596
W
D
T
Q
F
S
P
Y
G
Y
Y
F
V
S
G
Rhesus Macaque
Macaca mulatta
XP_001082212
589
66091
Y395
W
D
L
D
I
S
P
Y
S
L
Y
F
A
S
G
Dog
Lupus familis
XP_546100
589
66098
Y395
W
D
L
D
I
S
P
Y
S
L
Y
F
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WQ5
589
65892
F395
W
D
V
D
I
S
P
F
S
L
Y
F
A
S
G
Rat
Rattus norvegicus
NP_001100912
327
37201
D135
L
Q
N
A
S
Q
K
D
I
I
E
Q
L
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511993
623
70189
Y419
W
D
T
Q
F
S
P
Y
G
Y
Y
F
V
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5FWQ6
415
45899
I223
S
G
H
A
A
E
I
I
S
L
S
F
N
T
T
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
I223
A
G
H
F
A
E
I
I
S
L
C
F
N
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49846
704
79306
H503
W
D
V
R
F
A
P
H
G
Y
Y
F
V
S
C
Honey Bee
Apis mellifera
XP_001120374
605
67919
H402
W
C
V
R
F
S
P
H
G
Y
Y
F
A
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38129
798
88949
L578
W
D
V
S
F
S
P
L
G
H
Y
F
A
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.3
99.8
98.9
N.A.
93.3
51
N.A.
32.4
N.A.
20
20
N.A.
29.8
33.2
N.A.
N.A.
Protein Similarity:
100
46
99.8
99.1
N.A.
97.1
53.9
N.A.
49.7
N.A.
37.3
37.1
N.A.
48.8
52.7
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
86.6
0
N.A.
60
N.A.
20
20
N.A.
40
40
N.A.
N.A.
P-Site Similarity:
100
60
100
100
N.A.
100
6.6
N.A.
60
N.A.
26.6
26.6
N.A.
60
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
17
9
0
0
0
0
0
0
50
0
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% C
% Asp:
0
67
0
34
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
9
42
0
0
9
0
0
0
92
0
0
0
% F
% Gly:
0
17
0
0
0
0
0
0
42
0
0
0
0
0
50
% G
% His:
0
0
17
0
0
0
0
17
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
34
0
17
17
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
25
0
0
0
0
9
0
50
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
17
0
0
% N
% Pro:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
17
0
9
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
9
9
67
0
0
50
0
9
0
0
59
9
% S
% Thr:
0
0
17
0
0
0
0
0
0
0
0
0
0
34
25
% T
% Val:
0
0
34
0
0
0
0
0
0
0
0
0
25
0
0
% V
% Trp:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
34
75
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _