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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAF5L
All Species:
10
Human Site:
Y543
Identified Species:
20
UniProt:
O75529
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75529
NP_001020418.1
589
66155
Y543
V
W
D
I
R
N
T
Y
C
S
A
P
A
D
G
Chimpanzee
Pan troglodytes
XP_001135279
800
86826
F744
L
W
D
A
I
K
A
F
E
D
L
E
T
D
D
Rhesus Macaque
Macaca mulatta
XP_001082212
589
66091
Y543
V
W
D
I
R
N
T
Y
G
S
A
P
A
D
G
Dog
Lupus familis
XP_546100
589
66098
Y543
V
W
D
I
R
N
T
Y
C
S
T
P
A
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WQ5
589
65892
C543
V
W
D
I
R
S
T
C
C
N
T
P
A
D
G
Rat
Rattus norvegicus
NP_001100912
327
37201
L282
E
I
S
S
D
S
K
L
L
A
P
G
F
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511993
623
70189
F567
M
W
D
A
V
K
A
F
E
D
L
E
T
D
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5FWQ6
415
45899
R370
A
S
S
D
K
T
S
R
L
W
D
P
H
T
G
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
R370
A
S
V
D
K
T
S
R
V
W
C
V
K
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49846
704
79306
T651
L
W
D
F
H
K
V
T
E
D
Y
I
S
N
H
Honey Bee
Apis mellifera
XP_001120374
605
67919
A550
L
W
D
F
T
K
L
A
E
E
M
S
L
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38129
798
88949
A726
R
V
W
D
L
K
K
A
T
T
E
P
S
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.3
99.8
98.9
N.A.
93.3
51
N.A.
32.4
N.A.
20
20
N.A.
29.8
33.2
N.A.
N.A.
Protein Similarity:
100
46
99.8
99.1
N.A.
97.1
53.9
N.A.
49.7
N.A.
37.3
37.1
N.A.
48.8
52.7
N.A.
N.A.
P-Site Identity:
100
20
93.3
93.3
N.A.
73.3
6.6
N.A.
20
N.A.
13.3
6.6
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
33.3
93.3
93.3
N.A.
86.6
20
N.A.
33.3
N.A.
26.6
20
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
17
0
0
17
17
0
9
17
0
34
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
25
0
9
0
0
0
0
% C
% Asp:
0
0
67
25
9
0
0
0
0
25
9
0
0
59
25
% D
% Glu:
9
0
0
0
0
0
0
0
34
9
9
17
0
9
9
% E
% Phe:
0
0
0
17
0
0
0
17
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
50
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% H
% Ile:
0
9
0
34
9
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
17
42
17
0
0
0
0
0
9
0
0
% K
% Leu:
25
0
0
0
9
0
9
9
17
0
17
0
9
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
25
0
0
0
9
0
0
0
9
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
50
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
34
0
0
17
0
0
0
0
0
0
0
% R
% Ser:
0
17
17
9
0
17
17
0
0
25
0
9
17
0
0
% S
% Thr:
0
0
0
0
9
17
34
9
9
9
17
0
17
17
0
% T
% Val:
34
9
9
0
9
0
9
0
9
0
0
9
0
0
0
% V
% Trp:
0
67
9
0
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _