KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EED
All Species:
22.73
Human Site:
T50
Identified Species:
41.67
UniProt:
O75530
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75530
NP_003788.2
441
50198
T50
S
I
E
S
G
T
N
T
E
R
P
D
T
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102402
466
53042
T50
S
I
E
S
G
T
N
T
E
R
P
D
T
P
T
Dog
Lupus familis
XP_533985
466
53042
T50
S
I
E
S
G
T
N
T
E
R
P
D
T
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q921E6
441
50179
T50
S
I
E
S
G
T
N
T
E
R
P
D
T
P
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511506
448
50852
T57
S
I
E
S
G
T
N
T
E
R
P
D
T
P
T
Chicken
Gallus gallus
Q5ZKH3
446
50359
T55
S
I
E
S
G
T
N
T
E
R
P
D
T
P
T
Frog
Xenopus laevis
Q8UUP2
438
49707
P50
S
G
T
N
T
E
R
P
D
T
P
T
N
A
A
Zebra Danio
Brachydanio rerio
Q566T0
443
50598
P52
S
V
E
S
G
T
H
P
E
R
P
D
T
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24338
425
47969
R50
R
S
K
R
R
G
R
R
S
T
K
S
K
P
K
Honey Bee
Apis mellifera
XP_623808
427
48821
R50
P
T
R
S
A
R
Y
R
R
K
G
R
R
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786345
461
51844
P70
T
N
S
R
S
E
T
P
T
S
M
V
T
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8VZY6
379
42484
C12
G
P
G
Q
G
L
G
C
E
A
A
E
G
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT47
369
41239
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
94.6
N.A.
100
N.A.
N.A.
90.8
95.9
93.1
89.6
N.A.
49.8
56.2
N.A.
58.1
Protein Similarity:
100
N.A.
94.6
94.6
N.A.
100
N.A.
N.A.
92.4
97
96.1
95.2
N.A.
68.2
72.5
N.A.
73.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
100
13.3
80
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
100
26.6
93.3
N.A.
13.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
36.5
N.A.
34.6
N.A.
N.A.
Protein Similarity:
N.A.
54.4
N.A.
53
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
8
8
0
0
16
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
54
0
0
0
% D
% Glu:
0
0
54
0
0
16
0
0
62
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
62
8
8
0
0
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
8
8
0
8
0
8
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
47
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
0
0
0
0
0
24
0
0
62
0
0
62
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
16
8
8
16
16
8
54
0
8
8
8
0
% R
% Ser:
62
8
8
62
8
0
0
0
8
8
0
8
0
8
8
% S
% Thr:
8
8
8
0
8
54
8
47
8
16
0
8
62
0
54
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _