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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B1
All Species:
22.73
Human Site:
Y84
Identified Species:
41.67
UniProt:
O75533
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75533
NP_036565.2
1304
145830
Y84
L
G
Q
K
K
P
G
Y
H
A
P
V
A
L
L
Chimpanzee
Pan troglodytes
XP_516006
1379
153963
Y159
L
G
Q
K
K
P
G
Y
H
A
P
V
A
L
L
Rhesus Macaque
Macaca mulatta
XP_001086317
1397
156322
Y177
L
G
Q
K
K
P
G
Y
H
A
P
V
A
L
L
Dog
Lupus familis
XP_857149
1312
146628
Y84
L
G
Q
K
K
P
G
Y
H
A
P
V
A
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99NB9
1304
145798
Y84
L
G
Q
K
K
P
G
Y
H
A
P
V
A
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421912
1383
154834
H166
G
Q
K
K
P
G
Y
H
A
P
V
A
L
L
N
Frog
Xenopus laevis
O57683
1307
146196
A84
Q
K
K
P
G
Y
H
A
P
V
A
L
L
N
D
Zebra Danio
Brachydanio rerio
XP_684311
1315
147162
H87
V
Q
K
K
P
G
Y
H
A
P
V
A
I
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623732
1315
147662
A88
N
K
R
P
G
Y
T
A
P
A
A
L
L
N
D
Nematode Worm
Caenorhab. elegans
NP_497853
1322
147305
Y89
V
Q
K
K
S
T
N
Y
A
Q
P
H
K
F
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323970
1267
141858
V72
S
Y
T
A
P
K
S
V
L
K
E
M
P
R
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_201232
1269
141432
Y71
V
A
Q
R
L
A
S
Y
T
A
P
R
S
I
L
Baker's Yeast
Sacchar. cerevisiae
P49955
971
110009
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
93.3
99.3
N.A.
99.9
N.A.
N.A.
N.A.
93.7
96.6
93.7
N.A.
N.A.
82.4
65.1
N.A.
Protein Similarity:
100
94.5
93.3
99.3
N.A.
100
N.A.
N.A.
N.A.
93.7
98.3
96.4
N.A.
N.A.
88.9
76.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
26.6
13.3
33.3
N.A.
N.A.
20
40
N.A.
Percent
Protein Identity:
68.4
N.A.
N.A.
68.3
40.4
N.A.
Protein Similarity:
79.3
N.A.
N.A.
79.1
53.1
N.A.
P-Site Identity:
0
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
60
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
0
16
24
54
16
16
39
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
39
0
0
16
16
39
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
16
39
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% I
% Lys:
0
16
31
62
39
8
0
0
0
8
0
0
8
0
0
% K
% Leu:
39
0
0
0
8
0
0
0
8
0
0
16
24
54
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
0
16
16
% N
% Pro:
0
0
0
16
24
39
0
0
16
16
54
0
8
0
0
% P
% Gln:
8
24
47
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
8
0
0
0
8
0
16
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
8
8
0
8
0
0
0
0
0
0
% T
% Val:
24
0
0
0
0
0
0
8
0
8
16
39
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
16
16
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _