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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSDE1 All Species: 33.94
Human Site: T417 Identified Species: 67.88
UniProt: O75534 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75534 NP_001007554.1 798 88885 T417 I K K L P K G T V S F H S H S
Chimpanzee Pan troglodytes XP_001160588 856 95456 T475 I K K L P K G T V S F H S H S
Rhesus Macaque Macaca mulatta XP_001111655 844 93724 T463 I K K L P K G T V S F H S H S
Dog Lupus familis XP_533016 844 93644 T463 I K K L P K G T V S F H S H S
Cat Felis silvestris
Mouse Mus musculus Q91W50 798 88772 T417 I K K L P K G T V S F H S H S
Rat Rattus norvegicus P18395 798 88876 T417 I K K L P K G T V S F H S H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517851 687 76741 L337 R A T N I E V L S N T F Q C T
Chicken Gallus gallus NP_001026089 794 88641 G416 R I K K L P K G T V S F H T Q
Frog Xenopus laevis NP_001090026 781 87366 T370 I K K L P K G T V S F H T Q S
Zebra Danio Brachydanio rerio XP_002663174 798 88511 T416 I K K L P K G T V S F H T Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397449 890 99278 T515 L K H L P A G T V Q F E T I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789065 825 92298 G457 R I K R L P K G S V S F E T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.2 94.5 93.9 N.A. 98.5 98.6 N.A. 78.4 90.5 80.4 78.1 N.A. N.A. 38 N.A. 44.6
Protein Similarity: 100 93.2 94.5 94.1 N.A. 99.1 99.1 N.A. 82.7 94.4 87.4 88.2 N.A. N.A. 53.4 N.A. 62.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 6.6 86.6 86.6 N.A. N.A. 46.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 6.6 93.3 93.3 N.A. N.A. 60 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 9 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 75 25 0 0 0 % F
% Gly: 0 0 0 0 0 0 75 17 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 67 9 50 0 % H
% Ile: 67 17 0 0 9 0 0 0 0 0 0 0 0 9 9 % I
% Lys: 0 75 84 9 0 67 17 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 75 17 0 0 9 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 75 17 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 9 17 9 % Q
% Arg: 25 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 17 67 17 0 50 0 67 % S
% Thr: 0 0 9 0 0 0 0 75 9 0 9 0 25 17 9 % T
% Val: 0 0 0 0 0 0 9 0 75 17 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _