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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSDE1
All Species:
30.91
Human Site:
T595
Identified Species:
61.82
UniProt:
O75534
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75534
NP_001007554.1
798
88885
T595
I
T
E
E
A
D
P
T
I
Y
S
G
K
V
I
Chimpanzee
Pan troglodytes
XP_001160588
856
95456
T653
I
T
E
E
A
D
P
T
I
Y
S
G
K
V
I
Rhesus Macaque
Macaca mulatta
XP_001111655
844
93724
T641
I
T
E
E
A
D
P
T
I
Y
S
G
K
V
I
Dog
Lupus familis
XP_533016
844
93644
T641
I
T
E
E
A
D
P
T
I
Y
S
G
K
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91W50
798
88772
T595
I
T
E
E
A
N
P
T
I
Y
S
G
K
V
I
Rat
Rattus norvegicus
P18395
798
88876
T595
I
T
E
E
A
N
P
T
I
Y
S
G
K
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517851
687
76741
S514
V
R
L
L
G
R
N
S
N
A
K
R
L
L
G
Chicken
Gallus gallus
NP_001026089
794
88641
T593
I
T
E
E
A
D
P
T
V
Y
S
G
K
V
I
Frog
Xenopus laevis
NP_001090026
781
87366
M548
S
N
D
E
V
D
P
M
I
Y
W
G
K
V
V
Zebra Danio
Brachydanio rerio
XP_002663174
798
88511
T595
V
G
E
D
V
S
T
T
V
S
L
G
K
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397449
890
99278
E692
P
R
P
T
P
V
S
E
V
L
D
G
T
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789065
825
92298
H634
K
D
V
K
P
G
Q
H
N
G
T
V
I
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
94.5
93.9
N.A.
98.5
98.6
N.A.
78.4
90.5
80.4
78.1
N.A.
N.A.
38
N.A.
44.6
Protein Similarity:
100
93.2
94.5
94.1
N.A.
99.1
99.1
N.A.
82.7
94.4
87.4
88.2
N.A.
N.A.
53.4
N.A.
62.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
93.3
53.3
33.3
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
66.6
60
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
59
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
9
0
50
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
67
67
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
9
9
0
0
0
9
0
84
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
59
0
0
0
0
0
0
0
59
0
0
0
9
0
67
% I
% Lys:
9
0
0
9
0
0
0
0
0
0
9
0
75
0
0
% K
% Leu:
0
0
9
9
0
0
0
0
0
9
9
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
17
9
0
17
0
0
0
0
0
0
% N
% Pro:
9
0
9
0
17
0
67
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
0
0
0
9
0
0
0
0
0
9
0
9
0
% R
% Ser:
9
0
0
0
0
9
9
9
0
9
59
0
0
0
0
% S
% Thr:
0
59
0
9
0
0
9
67
0
0
9
0
9
0
0
% T
% Val:
17
0
9
0
17
9
0
0
25
0
0
9
0
84
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _