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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAB1 All Species: 10
Human Site: S308 Identified Species: 27.5
UniProt: O75553 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75553 NP_066566.3 588 63775 S308 G D A F I P S S S Q T L P A S
Chimpanzee Pan troglodytes XP_001155092 553 59609 G297 G T A A V P S G Y V A M G A V
Rhesus Macaque Macaca mulatta XP_001114475 553 59623 G297 S T A A V P S G Y V A M G A V
Dog Lupus familis XP_852920 678 73918 S398 G D A F I P S S S Q T L P A S
Cat Felis silvestris
Mouse Mus musculus P97318 588 63559 S308 G D A F L P S S S Q T L P G S
Rat Rattus norvegicus Q8CJH2 555 59882 G299 G T A A V P S G Y V A M G A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989569 551 59825 V296 V P F S T A A V P S G Y V A M
Frog Xenopus laevis NP_001083184 556 60125 S301 A Q Q W N P Q S L V F N Q P S
Zebra Danio Brachydanio rerio NP_001035775 588 63725 A308 T M G A V P P A W A Q Q Q F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 93.3 83.4 N.A. 94.7 91.3 N.A. N.A. 85.3 34.8 62.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93.8 93.5 84.6 N.A. 96.4 92.5 N.A. N.A. 88.9 51.8 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 33.3 26.6 100 N.A. 86.6 33.3 N.A. N.A. 6.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 46.6 40 100 N.A. 93.3 46.6 N.A. N.A. 13.3 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 67 45 0 12 12 12 0 12 34 0 0 67 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 12 34 0 0 0 0 0 0 12 0 0 12 0 % F
% Gly: 56 0 12 0 0 0 0 34 0 0 12 0 34 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 12 0 0 0 12 0 0 34 0 0 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 34 0 0 12 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 12 0 0 0 % N
% Pro: 0 12 0 0 0 89 12 0 12 0 0 0 34 12 0 % P
% Gln: 0 12 12 0 0 0 12 0 0 34 12 12 23 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 0 12 0 0 67 45 34 12 0 0 0 0 45 % S
% Thr: 12 34 0 0 12 0 0 0 0 0 34 0 0 0 0 % T
% Val: 12 0 0 0 45 0 0 12 0 45 0 0 12 0 34 % V
% Trp: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 34 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _