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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WBP4 All Species: 17.27
Human Site: S325 Identified Species: 34.55
UniProt: O75554 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75554 NP_009118.1 376 42507 S325 E N E Y V S T S E A D G G G E
Chimpanzee Pan troglodytes XP_509769 407 45876 S356 E N E Y V S T S E A D G G G E
Rhesus Macaque Macaca mulatta XP_001089735 375 42620 S324 E N E Y V S T S E A D G G G E
Dog Lupus familis XP_534136 371 42012 P322 E Y V S T S E P D I G G Q P K
Cat Felis silvestris
Mouse Mus musculus Q61048 376 42118 S326 E G E C L S T S E A G V G E I
Rat Rattus norvegicus Q5HZF2 374 42138 S324 E N E C L S S S E A G A G E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F457 398 45432 L337 D E K V D L E L P S T E G D S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018530 412 45135 G334 A R T T N P Y G A W E Q I Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608551 338 38769 S293 A P V V S A S S E P E P P V K
Honey Bee Apis mellifera XP_001121800 411 48183 P351 V F E K T E P P S I Q R T F K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782450 322 36118 Y276 Y V P Q A V Q Y E P R E K L K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151811 246 27219 V201 P A P S A V A V N K R K R D D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 96.5 88 N.A. 78.7 78.1 N.A. N.A. 52.7 N.A. 42.2 N.A. 30.5 30.1 N.A. 28.4
Protein Similarity: 100 91.8 97.8 94.1 N.A. 87.7 88.3 N.A. N.A. 66.8 N.A. 57.2 N.A. 49.4 47.6 N.A. 44.4
P-Site Identity: 100 100 100 20 N.A. 53.3 53.3 N.A. N.A. 6.6 N.A. 0 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 60 66.6 N.A. N.A. 26.6 N.A. 6.6 N.A. 40 13.3 N.A. 13.3
Percent
Protein Identity: N.A. 26 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 17 9 9 0 9 42 0 9 0 0 0 % A
% Cys: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 9 0 25 0 0 17 9 % D
% Glu: 50 9 50 0 0 9 17 0 59 0 17 17 0 17 25 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 9 0 0 0 0 0 9 0 0 25 34 50 25 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 17 0 0 9 0 25 % I
% Lys: 0 0 9 9 0 0 0 0 0 9 0 9 9 0 34 % K
% Leu: 0 0 0 0 17 9 0 9 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 34 0 0 9 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 9 9 17 0 0 9 9 17 9 17 0 9 9 9 0 % P
% Gln: 0 0 0 9 0 0 9 0 0 0 9 9 9 9 0 % Q
% Arg: 0 9 0 0 0 0 0 0 0 0 17 9 9 0 0 % R
% Ser: 0 0 0 17 9 50 17 50 9 9 0 0 0 0 9 % S
% Thr: 0 0 9 9 17 0 34 0 0 0 9 0 9 0 0 % T
% Val: 9 9 17 17 25 17 0 9 0 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 9 9 0 25 0 0 9 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _