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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WBP4 All Species: 12.42
Human Site: T244 Identified Species: 24.85
UniProt: O75554 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75554 NP_009118.1 376 42507 T244 E G G V S T E T E K P K I K F
Chimpanzee Pan troglodytes XP_509769 407 45876 T275 E G G V S A E T E K P K I K F
Rhesus Macaque Macaca mulatta XP_001089735 375 42620 T243 E G E V S T E T Q K P K I K F
Dog Lupus familis XP_534136 371 42012 T241 K G E A S T E T Q K P K I K F
Cat Felis silvestris
Mouse Mus musculus Q61048 376 42118 K245 G E A S T E T K K L I I K F K
Rat Rattus norvegicus Q5HZF2 374 42138 K243 G E A S A E T K K L I I K F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F457 398 45432 E256 T N L K R K G E N D E E S E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018530 412 45135 N253 D T A E A D D N T P S S G P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608551 338 38769 N212 E S L K F R A N V D E E V A R
Honey Bee Apis mellifera XP_001121800 411 48183 R270 R A N A E R E R M K E L R K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782450 322 36118 K195 P A N F T S S K D K S S S K G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151811 246 27219 N120 T G L Y Y D S N S G F Y Y S D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 96.5 88 N.A. 78.7 78.1 N.A. N.A. 52.7 N.A. 42.2 N.A. 30.5 30.1 N.A. 28.4
Protein Similarity: 100 91.8 97.8 94.1 N.A. 87.7 88.3 N.A. N.A. 66.8 N.A. 57.2 N.A. 49.4 47.6 N.A. 44.4
P-Site Identity: 100 93.3 86.6 73.3 N.A. 0 0 N.A. N.A. 0 N.A. 0 N.A. 6.6 20 N.A. 13.3
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 13.3 13.3 N.A. N.A. 13.3 N.A. 20 N.A. 20 20 N.A. 33.3
Percent
Protein Identity: N.A. 26 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 25 17 17 9 9 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 17 9 0 9 17 0 0 0 0 9 % D
% Glu: 34 17 17 9 9 17 42 9 17 0 25 17 0 9 0 % E
% Phe: 0 0 0 9 9 0 0 0 0 0 9 0 0 17 34 % F
% Gly: 17 42 17 0 0 0 9 0 0 9 0 0 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 17 17 34 0 9 % I
% Lys: 9 0 0 17 0 9 0 25 17 50 0 34 17 50 34 % K
% Leu: 0 0 25 0 0 0 0 0 0 17 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 9 17 0 0 0 0 25 9 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 9 34 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 9 17 0 9 0 0 0 0 9 0 9 % R
% Ser: 0 9 0 17 34 9 17 0 9 0 17 17 17 9 0 % S
% Thr: 17 9 0 0 17 25 17 34 9 0 0 0 0 0 0 % T
% Val: 0 0 0 25 0 0 0 0 9 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 0 0 0 0 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _