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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKAP2
All Species:
17.27
Human Site:
S223
Identified Species:
34.55
UniProt:
O75563
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75563
NP_003921.2
359
41217
S223
F
V
L
Q
D
M
E
S
D
I
I
P
E
D
Y
Chimpanzee
Pan troglodytes
XP_519007
359
41182
S223
F
V
L
Q
D
M
E
S
D
I
I
P
E
D
Y
Rhesus Macaque
Macaca mulatta
XP_001093819
359
41214
S223
F
V
L
Q
D
M
E
S
D
I
I
P
E
D
Y
Dog
Lupus familis
XP_539483
359
41016
S223
F
V
L
Q
D
M
G
S
D
V
I
P
E
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UND0
358
40694
G222
K
F
I
L
Q
D
L
G
S
D
V
I
P
E
D
Rat
Rattus norvegicus
Q920G0
358
40698
G222
K
F
I
L
Q
D
M
G
S
D
V
I
P
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510350
405
47055
S269
F
V
L
Q
D
M
E
S
D
I
I
P
E
D
D
Chicken
Gallus gallus
XP_418727
336
38563
Q204
K
E
A
E
E
W
V
Q
Q
V
K
F
V
I
Q
Frog
Xenopus laevis
Q5XGP7
330
38030
E198
S
S
P
K
E
A
E
E
W
I
N
V
I
M
N
Zebra Danio
Brachydanio rerio
Q6PG29
341
39166
D209
H
I
D
F
L
I
K
D
L
G
G
I
I
P
E
Tiger Blowfish
Takifugu rubipres
Q1KKZ1
329
37922
E197
S
S
V
K
E
A
E
E
W
V
K
Q
I
D
F
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785357
472
53444
P336
H
G
A
L
P
E
V
P
H
T
P
S
Q
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.3
93.5
N.A.
90.5
87.7
N.A.
73
71.3
60.4
58.7
58.5
N.A.
N.A.
N.A.
27.3
Protein Similarity:
100
99.7
98.8
95.8
N.A.
94.7
93.8
N.A.
80
81.6
75.2
73.8
70.7
N.A.
N.A.
N.A.
43.2
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
93.3
0
13.3
0
13.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
20
20
N.A.
93.3
20
26.6
20
46.6
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
17
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
42
17
0
9
42
17
0
0
0
50
34
% D
% Glu:
0
9
0
9
25
9
50
17
0
0
0
0
42
17
9
% E
% Phe:
42
17
0
9
0
0
0
0
0
0
0
9
0
0
9
% F
% Gly:
0
9
0
0
0
0
9
17
0
9
9
0
0
0
0
% G
% His:
17
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
17
0
0
9
0
0
0
42
42
25
25
9
0
% I
% Lys:
25
0
0
17
0
0
9
0
0
0
17
0
0
0
0
% K
% Leu:
0
0
42
25
9
0
9
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
42
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% N
% Pro:
0
0
9
0
9
0
0
9
0
0
9
42
17
17
0
% P
% Gln:
0
0
0
42
17
0
0
9
9
0
0
9
9
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
17
0
0
0
0
0
42
17
0
0
9
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
42
9
0
0
0
17
0
0
25
17
9
9
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
17
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _