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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKRA
All Species:
15.76
Human Site:
S196
Identified Species:
34.67
UniProt:
O75569
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75569
NP_001132989.1
313
34404
S196
L
A
K
F
S
N
I
S
P
E
N
H
I
S
L
Chimpanzee
Pan troglodytes
XP_001156031
270
29651
P154
A
K
F
S
N
I
S
P
E
N
H
I
S
L
T
Rhesus Macaque
Macaca mulatta
XP_001098583
302
33088
P186
A
K
F
S
N
I
S
P
E
N
H
I
S
L
T
Dog
Lupus familis
XP_545545
313
34342
S196
L
A
K
F
S
N
I
S
P
E
N
H
I
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX2
313
34353
S196
L
A
K
F
S
N
I
S
P
E
N
H
I
S
L
Rat
Rattus norvegicus
Q4V8C7
313
34337
S196
L
A
K
F
S
N
I
S
P
E
N
H
I
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515387
397
42380
T280
L
A
K
L
H
T
V
T
A
G
Q
K
K
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYA5
309
34051
I192
L
L
T
K
F
K
T
I
S
T
D
N
I
P
L
Zebra Danio
Brachydanio rerio
B0V3F8
282
30822
Q166
E
N
M
I
A
K
L
Q
S
L
S
G
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624606
338
37626
G222
V
L
K
Y
R
E
V
G
Q
G
K
S
K
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797998
306
33757
L190
H
R
L
S
I
K
N
L
P
Q
A
E
G
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
95.2
99.3
N.A.
98
97.7
N.A.
51.3
N.A.
61.3
47.9
N.A.
N.A.
22.4
N.A.
35.4
Protein Similarity:
100
86.2
95.2
99.6
N.A.
99.3
99.3
N.A.
64.4
N.A.
75.4
63.2
N.A.
N.A.
40.2
N.A.
49.8
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
33.3
N.A.
20
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
46.6
N.A.
33.3
26.6
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
46
0
0
10
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
0
19
37
0
10
0
0
10
% E
% Phe:
0
0
19
37
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
10
0
19
0
10
10
0
0
% G
% His:
10
0
0
0
10
0
0
0
0
0
19
37
0
0
0
% H
% Ile:
0
0
0
10
10
19
37
10
0
0
0
19
46
0
0
% I
% Lys:
0
19
55
10
0
28
0
0
0
0
10
10
19
10
0
% K
% Leu:
55
19
10
10
0
0
10
10
0
10
0
0
0
19
55
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
19
37
10
0
0
19
37
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
19
46
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
10
10
0
0
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
28
37
0
19
37
19
0
10
10
28
55
0
% S
% Thr:
0
0
10
0
0
10
10
10
0
10
0
0
0
0
19
% T
% Val:
10
0
0
0
0
0
19
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _