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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKRA All Species: 13.64
Human Site: Y52 Identified Species: 30
UniProt: O75569 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75569 NP_001132989.1 313 34404 Y52 K T K N I P V Y E C E R S D V
Chimpanzee Pan troglodytes XP_001156031 270 29651 I18 C E R S D V Q I H V P T F T F
Rhesus Macaque Macaca mulatta XP_001098583 302 33088 I50 C E R S D V Q I H V P T F T F
Dog Lupus familis XP_545545 313 34342 Y52 K T K N I P V Y E C E R S D V
Cat Felis silvestris
Mouse Mus musculus Q9WTX2 313 34353 Y52 K T K N I P V Y E C E R S D V
Rat Rattus norvegicus Q4V8C7 313 34337 Y52 K T K N I P V Y E C E R S D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515387 397 42380 F136 K T G F V P V F E C E K A E G
Chicken Gallus gallus
Frog Xenopus laevis Q7ZYA5 309 34051 E52 N H P V Y T L E K A E G Q A H
Zebra Danio Brachydanio rerio B0V3F8 282 30822 L30 S S A P K Y E L I H A D G D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624606 338 37626 P54 S L M I G K R P I S E A A Q L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797998 306 33757 G53 D V V G N G Q G P S K K V A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 95.2 99.3 N.A. 98 97.7 N.A. 51.3 N.A. 61.3 47.9 N.A. N.A. 22.4 N.A. 35.4
Protein Similarity: 100 86.2 95.2 99.6 N.A. 99.3 99.3 N.A. 64.4 N.A. 75.4 63.2 N.A. N.A. 40.2 N.A. 49.8
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 46.6 N.A. 6.6 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 13.3 13.3 100 N.A. 100 100 N.A. 80 N.A. 20 13.3 N.A. N.A. 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 10 10 10 19 19 10 % A
% Cys: 19 0 0 0 0 0 0 0 0 46 0 0 0 0 0 % C
% Asp: 10 0 0 0 19 0 0 0 0 0 0 10 0 46 0 % D
% Glu: 0 19 0 0 0 0 10 10 46 0 64 0 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 10 0 0 0 0 19 0 19 % F
% Gly: 0 0 10 10 10 10 0 10 0 0 0 10 10 0 10 % G
% His: 0 10 0 0 0 0 0 0 19 10 0 0 0 0 10 % H
% Ile: 0 0 0 10 37 0 0 19 19 0 0 0 0 0 0 % I
% Lys: 46 0 37 0 10 10 0 0 10 0 10 19 0 0 10 % K
% Leu: 0 10 0 0 0 0 10 10 0 0 0 0 0 0 10 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 37 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 10 0 46 0 10 10 0 19 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 28 0 0 0 0 0 10 10 0 % Q
% Arg: 0 0 19 0 0 0 10 0 0 0 0 37 0 0 0 % R
% Ser: 19 10 0 19 0 0 0 0 0 19 0 0 37 0 0 % S
% Thr: 0 46 0 0 0 10 0 0 0 0 0 19 0 19 0 % T
% Val: 0 10 10 10 10 19 46 0 0 19 0 0 10 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 10 0 37 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _