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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTRF1
All Species:
22.73
Human Site:
T277
Identified Species:
55.56
UniProt:
O75570
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75570
NP_004285.2
445
52306
T277
S
R
M
Q
R
I
H
T
G
T
M
S
V
I
V
Chimpanzee
Pan troglodytes
XP_001150094
487
56725
T319
S
R
M
Q
R
I
H
T
G
T
M
S
V
I
V
Rhesus Macaque
Macaca mulatta
XP_001090893
445
52378
T277
S
R
M
Q
R
I
H
T
G
T
M
S
V
I
V
Dog
Lupus familis
XP_848713
444
51918
T276
A
R
M
Q
R
I
H
T
G
T
M
S
V
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K126
446
52439
T278
S
R
M
Q
R
I
H
T
G
T
M
S
V
I
V
Rat
Rattus norvegicus
Q4V7E5
373
42325
I227
P
T
E
I
K
L
V
I
N
P
K
D
L
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510216
380
43443
I234
P
T
E
I
N
L
V
I
H
P
K
D
L
R
I
Chicken
Gallus gallus
XP_417026
455
52812
T284
S
R
M
Q
R
I
H
T
G
T
M
S
V
I
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001012512
235
27291
I89
M
E
E
V
D
I
D
I
A
P
K
D
L
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797931
422
47503
E263
A
V
L
P
Q
P
K
E
I
D
L
K
L
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.3
97
86.7
N.A.
81.8
40.4
N.A.
40.6
63
N.A.
35.9
N.A.
N.A.
N.A.
N.A.
37.3
Protein Similarity:
100
91.3
98.4
92.5
N.A.
89.4
57.2
N.A.
57.9
77.3
N.A.
44
N.A.
N.A.
N.A.
N.A.
56.6
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
0
100
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
20
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
0
10
0
30
0
10
0
% D
% Glu:
0
10
30
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
60
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
70
0
30
10
0
0
0
0
60
30
% I
% Lys:
0
0
0
0
10
0
10
0
0
0
30
10
0
0
0
% K
% Leu:
0
0
10
0
0
20
0
0
0
0
10
0
40
0
0
% L
% Met:
10
0
60
0
0
0
0
0
0
0
60
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
20
0
0
10
0
10
0
0
0
30
0
0
0
0
10
% P
% Gln:
0
0
0
60
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
60
0
0
60
0
0
0
0
0
0
0
0
30
0
% R
% Ser:
50
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% S
% Thr:
0
20
0
0
0
0
0
60
0
60
0
0
0
0
0
% T
% Val:
0
10
0
10
0
0
20
0
0
0
0
0
60
0
60
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _