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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTRF1 All Species: 11.21
Human Site: Y18 Identified Species: 27.41
UniProt: O75570 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75570 NP_004285.2 445 52306 Y18 R H P S L N G Y L Q C H I Q L
Chimpanzee Pan troglodytes XP_001150094 487 56725 Y18 R H P S L N G Y L Q C H I Q L
Rhesus Macaque Macaca mulatta XP_001090893 445 52378 Y18 R H P S L N G Y L Q C H I Q L
Dog Lupus familis XP_848713 444 51918 L15 W L F R C L S L N G R H I H P
Cat Felis silvestris
Mouse Mus musculus Q8K126 446 52439 C18 R N P F L R A C P Q R H V F L
Rat Rattus norvegicus Q4V7E5 373 42325
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510216 380 43443
Chicken Gallus gallus XP_417026 455 52812 Y18 K N L L S S C Y C Y G Q L H N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001012512 235 27291
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797931 422 47503 T12 G S S A G N K T G D P L S P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.3 97 86.7 N.A. 81.8 40.4 N.A. 40.6 63 N.A. 35.9 N.A. N.A. N.A. N.A. 37.3
Protein Similarity: 100 91.3 98.4 92.5 N.A. 89.4 57.2 N.A. 57.9 77.3 N.A. 44 N.A. N.A. N.A. N.A. 56.6
P-Site Identity: 100 100 100 13.3 N.A. 40 0 N.A. 0 6.6 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 13.3 N.A. 53.3 0 N.A. 0 33.3 N.A. 0 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 10 10 10 0 30 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 10 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 10 0 0 0 10 0 30 0 10 10 10 0 0 0 0 % G
% His: 0 30 0 0 0 0 0 0 0 0 0 50 0 20 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % I
% Lys: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 10 10 40 10 0 10 30 0 0 10 10 0 40 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 0 40 0 0 10 0 0 0 0 0 10 % N
% Pro: 0 0 40 0 0 0 0 0 10 0 10 0 0 10 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 40 0 10 0 30 0 % Q
% Arg: 40 0 0 10 0 10 0 0 0 0 20 0 0 0 0 % R
% Ser: 0 10 10 30 10 10 10 0 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _