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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGA10
All Species:
25.15
Human Site:
Y749
Identified Species:
69.17
UniProt:
O75578
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75578
NP_003628.2
1167
127602
Y749
H
V
L
D
T
S
D
Y
L
R
P
V
A
L
T
Chimpanzee
Pan troglodytes
XP_514418
1167
127557
Y749
H
V
L
D
T
S
D
Y
L
R
P
V
A
L
T
Rhesus Macaque
Macaca mulatta
XP_001083531
1185
132998
Y739
H
V
L
D
T
A
D
Y
V
K
P
V
T
F
S
Dog
Lupus familis
XP_850355
1165
127528
Y749
H
V
L
D
T
S
D
Y
L
R
P
L
A
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P61622
1188
132994
Y742
H
V
L
D
T
A
D
Y
V
K
P
V
A
F
S
Rat
Rattus norvegicus
P18614
1180
130790
D770
L
D
K
H
D
F
Q
D
S
V
R
V
T
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516049
1194
133034
Y748
H
V
L
D
T
A
D
Y
V
K
P
V
A
F
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91687
1032
115197
G652
S
K
T
Y
L
A
V
G
G
M
K
S
L
M
I
Zebra Danio
Brachydanio rerio
NP_001166098
1190
134079
Y746
H
V
M
E
T
T
D
Y
A
R
P
I
I
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
41.8
92
N.A.
43.5
36.4
N.A.
44.1
N.A.
24.5
43.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
59.5
95.8
N.A.
61.2
56.6
N.A.
62
N.A.
41.2
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
93.3
N.A.
66.6
13.3
N.A.
66.6
N.A.
0
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
93.3
13.3
N.A.
93.3
N.A.
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
45
0
0
12
0
0
0
56
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
67
12
0
78
12
0
0
0
0
0
0
12
% D
% Glu:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
45
0
% F
% Gly:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% G
% His:
78
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
12
% I
% Lys:
0
12
12
0
0
0
0
0
0
34
12
0
0
0
0
% K
% Leu:
12
0
67
0
12
0
0
0
34
0
0
12
12
45
0
% L
% Met:
0
0
12
0
0
0
0
0
0
12
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
45
12
0
0
0
0
% R
% Ser:
12
0
0
0
0
34
0
0
12
0
0
12
0
0
34
% S
% Thr:
0
0
12
0
78
12
0
0
0
0
0
0
23
0
45
% T
% Val:
0
78
0
0
0
0
12
0
34
12
0
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _