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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
21.21
Human Site:
S268
Identified Species:
31.11
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S268
K
N
S
Q
A
E
I
S
R
R
I
L
K
S
E
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S360
K
N
S
Q
A
E
I
S
R
R
I
L
K
S
E
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S526
K
N
S
Q
A
E
I
S
R
R
I
L
K
S
E
Dog
Lupus familis
XP_547953
806
90703
S275
K
N
S
Q
A
E
I
S
R
R
I
L
K
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
Q274
P
V
A
Q
D
L
L
Q
R
L
L
C
K
D
P
Rat
Rattus norvegicus
Q63531
735
82865
K278
M
T
L
I
L
K
A
K
L
G
M
P
Q
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
D261
P
V
I
R
D
E
L
D
V
S
N
F
A
E
E
Chicken
Gallus gallus
Q5F3L1
789
89022
Q281
A
L
S
K
D
I
I
Q
R
L
L
M
K
D
P
Frog
Xenopus laevis
P10665
733
82620
K278
M
T
L
I
L
K
A
K
L
G
M
P
Q
F
L
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
K283
M
N
M
I
L
K
A
K
L
G
M
P
Q
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S480
Q
V
Q
Q
S
E
I
S
R
R
I
Q
K
E
Q
Honey Bee
Apis mellifera
XP_395099
910
102507
S286
K
N
T
Q
Q
D
I
S
R
R
I
L
K
T
D
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
R269
L
E
K
K
L
E
K
R
L
G
Y
N
G
V
D
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
I270
G
C
N
G
V
K
D
I
K
S
H
S
F
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Q40
L
G
D
N
L
E
L
Q
F
S
D
V
F
G
P
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
F246
D
V
T
R
K
L
R
F
L
K
I
D
V
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
20
0
N.A.
13.3
26.6
0
6.6
N.A.
53.3
66.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
40
20
N.A.
26.6
46.6
20
26.6
N.A.
73.3
93.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
25
0
19
0
0
0
0
0
7
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
7
0
7
0
19
7
7
7
0
0
7
7
0
13
13
% D
% Glu:
0
7
0
0
0
50
0
0
0
0
0
0
0
13
32
% E
% Phe:
0
0
0
0
0
0
0
7
7
0
0
7
13
32
0
% F
% Gly:
7
7
0
7
0
0
0
0
0
25
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
7
19
0
7
44
7
0
0
44
0
0
0
0
% I
% Lys:
32
0
7
13
7
25
7
19
7
7
0
0
50
0
7
% K
% Leu:
13
7
13
0
32
13
19
0
32
13
13
32
0
0
19
% L
% Met:
19
0
7
0
0
0
0
0
0
0
19
7
0
0
0
% M
% Asn:
0
38
7
7
0
0
0
0
0
0
7
7
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
19
0
0
19
% P
% Gln:
7
0
7
44
7
0
0
19
0
0
0
7
19
0
7
% Q
% Arg:
0
0
0
13
0
0
7
7
50
38
0
0
0
0
0
% R
% Ser:
0
0
32
0
7
0
0
38
0
19
0
7
0
25
0
% S
% Thr:
0
13
13
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
25
0
0
7
0
0
0
7
0
0
7
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _