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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
25.45
Human Site:
S346
Identified Species:
37.33
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S346
I
R
D
E
L
D
V
S
N
F
A
E
E
F
T
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S438
I
R
D
E
L
D
V
S
N
F
A
E
E
F
T
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S604
I
R
D
E
L
D
V
S
N
F
A
E
E
F
T
Dog
Lupus familis
XP_547953
806
90703
S353
I
R
D
E
L
D
V
S
N
F
A
E
E
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
G329
I
R
S
E
L
D
V
G
N
F
A
E
E
F
T
Rat
Rattus norvegicus
Q63531
735
82865
G308
P
A
N
R
L
G
S
G
P
D
G
A
E
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
G291
S
S
E
R
I
F
Q
G
Y
S
F
V
A
P
S
Chicken
Gallus gallus
Q5F3L1
789
89022
S336
I
R
D
E
L
D
V
S
N
F
A
E
E
F
T
Frog
Xenopus laevis
P10665
733
82620
A308
P
T
N
R
L
G
S
A
M
E
G
A
E
E
I
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
I320
G
P
D
G
V
E
E
I
K
R
H
T
F
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
Q558
L
T
A
E
D
D
V
Q
N
F
S
N
E
F
T
Honey Bee
Apis mellifera
XP_395099
910
102507
S368
I
A
H
E
L
D
T
S
N
F
S
D
E
F
T
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
Q312
I
G
H
D
L
D
T
Q
F
F
S
A
E
F
T
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S304
I
N
G
E
L
D
T
S
N
F
A
E
E
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
R70
E
P
A
V
V
Y
S
R
S
H
S
L
V
G
P
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
L276
I
G
E
Q
D
E
V
L
K
E
I
L
K
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
0
100
13.3
13.3
N.A.
53.3
66.6
46.6
80
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
20
100
26.6
33.3
N.A.
66.6
80
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
0
0
0
0
7
0
0
44
19
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
38
7
13
63
0
0
0
7
0
7
0
0
0
% D
% Glu:
7
0
13
57
0
13
7
0
0
13
0
44
75
13
0
% E
% Phe:
0
0
0
0
0
7
0
0
7
63
7
0
7
69
0
% F
% Gly:
7
13
7
7
0
13
0
19
0
0
13
0
0
7
0
% G
% His:
0
0
13
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
63
0
0
0
7
0
0
7
0
0
7
0
0
0
19
% I
% Lys:
0
0
0
0
0
0
0
0
13
0
0
0
7
7
0
% K
% Leu:
7
0
0
0
69
0
0
7
0
0
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
13
0
0
0
0
0
57
0
0
7
0
0
0
% N
% Pro:
13
13
0
0
0
0
0
0
7
0
0
0
0
7
7
% P
% Gln:
0
0
0
7
0
0
7
13
0
0
0
0
0
0
0
% Q
% Arg:
0
38
0
19
0
0
0
7
0
7
0
0
0
0
0
% R
% Ser:
7
7
7
0
0
0
19
44
7
7
25
0
0
0
13
% S
% Thr:
0
13
0
0
0
0
19
0
0
0
0
7
0
0
63
% T
% Val:
0
0
0
7
13
0
50
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _