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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
33.94
Human Site:
S438
Identified Species:
49.78
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S438
P
L
G
E
G
S
F
S
I
C
R
K
C
V
H
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S530
P
L
G
E
G
S
F
S
I
C
R
K
C
V
H
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S690
P
L
G
E
G
S
F
S
I
C
R
K
C
V
H
Dog
Lupus familis
XP_547953
806
90703
S445
P
L
G
E
G
S
F
S
I
C
R
K
C
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S423
A
L
G
Q
G
S
F
S
V
C
R
R
C
R
Q
Rat
Rattus norvegicus
Q63531
735
82865
S391
T
G
L
M
E
D
D
S
K
P
R
A
T
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
I373
N
Q
E
Y
A
V
K
I
I
S
K
R
M
E
A
Chicken
Gallus gallus
Q5F3L1
789
89022
S428
P
L
G
E
G
S
F
S
I
C
R
K
C
L
H
Frog
Xenopus laevis
P10665
733
82620
V399
K
K
T
S
S
P
P
V
L
S
V
P
K
T
H
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
I403
K
S
A
P
L
V
N
I
L
P
I
V
Q
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
D646
F
V
V
D
S
S
T
D
L
V
F
L
A
K
I
Honey Bee
Apis mellifera
XP_395099
910
102507
S463
A
L
G
D
G
S
F
S
V
C
R
K
C
R
H
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
S394
L
L
G
K
G
A
F
S
V
V
R
R
C
E
R
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S397
P
I
G
D
G
S
F
S
I
C
R
R
C
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
G152
V
V
G
Q
G
A
F
G
K
V
Y
Q
V
R
K
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
V358
G
K
G
S
F
G
K
V
M
Q
V
R
K
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
93.3
N.A.
60
13.3
N.A.
6.6
93.3
6.6
13.3
N.A.
6.6
73.3
46.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
80
13.3
N.A.
20
100
13.3
20
N.A.
26.6
86.6
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
0
7
13
0
0
0
0
0
7
7
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
0
0
57
0
0
% C
% Asp:
0
0
0
19
0
7
7
7
0
0
0
0
0
0
7
% D
% Glu:
0
0
7
32
7
0
0
0
0
0
0
0
0
13
0
% E
% Phe:
7
0
0
0
7
0
63
0
0
0
7
0
0
0
0
% F
% Gly:
7
7
69
0
63
7
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
57
% H
% Ile:
0
7
0
0
0
0
0
13
44
0
7
0
0
7
7
% I
% Lys:
13
13
0
7
0
0
13
0
13
0
7
38
13
13
7
% K
% Leu:
7
50
7
0
7
0
0
0
19
0
0
7
0
7
0
% L
% Met:
0
0
0
7
0
0
0
0
7
0
0
0
7
0
0
% M
% Asn:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
38
0
0
7
0
7
7
0
0
13
0
7
0
0
0
% P
% Gln:
0
7
0
13
0
0
0
0
0
7
0
7
7
7
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
63
32
0
19
7
% R
% Ser:
0
7
0
13
13
57
0
63
0
13
0
0
0
0
0
% S
% Thr:
7
0
7
0
0
0
7
0
0
0
0
0
7
13
0
% T
% Val:
7
13
7
0
0
13
0
13
19
19
13
7
7
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _