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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
32.73
Human Site:
S657
Identified Species:
48
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S657
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S749
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S909
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Dog
Lupus familis
XP_547953
806
90703
S664
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
F633
C
K
I
R
E
G
R
F
S
L
D
G
E
A
W
Rat
Rattus norvegicus
Q63531
735
82865
K587
F
V
A
P
E
V
L
K
R
Q
G
Y
D
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S574
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Chicken
Gallus gallus
Q5F3L1
789
89022
S647
G
E
A
W
K
N
V
S
E
E
A
K
E
L
I
Frog
Xenopus laevis
P10665
733
82620
G592
K
R
Q
G
Y
D
E
G
C
D
I
W
S
L
G
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
V604
C
D
I
W
S
L
G
V
L
L
Y
T
M
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S856
S
M
R
W
E
S
A
S
P
A
F
R
H
L
V
Honey Bee
Apis mellifera
XP_395099
910
102507
K676
N
L
A
R
Q
V
A
K
G
L
L
T
V
D
P
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
S623
G
D
A
W
T
N
V
S
A
D
A
K
N
L
I
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S617
G
E
E
W
N
S
V
S
T
P
A
K
D
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
P336
E
M
L
T
G
K
P
P
F
L
G
S
K
G
K
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
Y542
M
M
T
G
L
P
P
Y
Y
D
E
N
V
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
0
13.3
N.A.
100
86.6
6.6
13.3
N.A.
20
6.6
66.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
20
40
N.A.
100
100
20
20
N.A.
46.6
13.3
86.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
57
0
0
0
13
0
7
7
50
0
0
7
7
% A
% Cys:
13
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
7
0
0
0
19
7
0
44
7
0
% D
% Glu:
7
44
7
0
19
0
7
0
7
38
7
0
13
7
0
% E
% Phe:
7
0
0
0
0
0
0
7
7
0
7
0
0
0
0
% F
% Gly:
50
0
0
13
7
7
7
7
7
0
13
7
0
7
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
0
7
0
0
0
50
% I
% Lys:
7
7
0
0
38
7
0
13
0
0
0
50
7
0
7
% K
% Leu:
0
7
7
0
7
7
7
0
7
25
7
0
0
69
0
% L
% Met:
7
19
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
0
0
7
44
0
0
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
7
0
7
13
7
7
7
0
0
0
7
7
% P
% Gln:
0
0
7
0
7
0
0
0
32
7
0
0
0
0
0
% Q
% Arg:
0
7
7
13
0
0
7
0
7
0
0
7
0
0
0
% R
% Ser:
7
0
0
0
7
13
0
57
7
0
0
7
7
0
0
% S
% Thr:
0
0
7
7
7
0
0
0
7
0
0
13
0
0
0
% T
% Val:
0
7
0
0
0
13
50
7
0
0
0
0
13
0
13
% V
% Trp:
0
0
0
63
0
0
0
0
0
0
0
7
0
0
7
% W
% Tyr:
0
0
0
0
7
0
0
7
7
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _