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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
26.67
Human Site:
S691
Identified Species:
39.11
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S691
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
L
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S783
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
L
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S943
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
L
Dog
Lupus familis
XP_547953
806
90703
S698
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
G667
A
K
R
L
K
L
E
G
L
R
S
S
S
W
L
Rat
Rattus norvegicus
Q63531
735
82865
T621
F
A
N
G
P
S
D
T
P
E
E
I
L
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S608
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
L
Chicken
Gallus gallus
Q5F3L1
789
89022
S681
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
L
Frog
Xenopus laevis
P10665
733
82620
R626
T
P
E
E
I
L
A
R
I
G
S
G
K
F
T
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
L638
I
G
S
G
K
F
S
L
S
G
G
N
W
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S890
S
E
W
L
Q
Y
G
S
N
D
P
D
V
D
I
Honey Bee
Apis mellifera
XP_395099
910
102507
Y710
S
F
D
V
A
S
S
Y
D
V
N
V
L
D
N
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
A657
H
M
W
L
K
S
S
A
S
M
D
T
P
L
Q
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
Q651
N
E
W
I
Q
G
Q
Q
L
S
T
S
T
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
L370
A
H
A
L
L
K
G
L
L
Q
K
E
P
E
R
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
L576
A
K
D
L
L
I
G
L
L
S
R
D
P
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
26.6
0
N.A.
100
100
6.6
0
N.A.
40
0
13.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
46.6
6.6
N.A.
100
100
6.6
13.3
N.A.
53.3
26.6
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
7
0
7
0
7
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
38
7
0
7
7
7
13
0
19
0
% D
% Glu:
0
50
7
7
0
0
7
0
0
7
7
7
0
7
0
% E
% Phe:
7
7
0
0
0
7
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
7
0
13
0
7
57
7
0
13
7
7
0
0
0
% G
% His:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
7
7
0
0
7
0
0
7
0
0
7
% I
% Lys:
0
13
0
0
19
7
0
0
0
0
7
0
7
0
0
% K
% Leu:
0
0
0
69
13
13
0
19
25
38
0
0
13
7
50
% L
% Met:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
44
0
7
0
0
0
0
0
7
0
7
7
38
0
7
% N
% Pro:
0
7
0
0
7
0
0
0
7
0
7
0
19
44
0
% P
% Gln:
0
0
0
0
50
0
7
7
38
7
0
0
0
0
7
% Q
% Arg:
0
0
7
0
0
0
0
7
0
7
7
0
0
0
19
% R
% Ser:
13
0
7
0
0
19
19
44
13
13
50
50
7
7
7
% S
% Thr:
7
0
0
0
0
0
0
7
0
0
7
7
7
7
7
% T
% Val:
0
0
0
7
0
0
0
0
0
7
0
7
7
0
0
% V
% Trp:
0
0
57
0
0
0
0
0
0
0
0
0
7
7
0
% W
% Tyr:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _