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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
25.45
Human Site:
S768
Identified Species:
37.33
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S768
E
S
S
H
S
S
S
S
H
S
H
G
K
T
T
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S860
E
S
S
H
S
S
S
S
H
S
H
G
K
T
T
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S1020
E
S
S
H
S
S
S
S
H
S
H
G
K
T
T
Dog
Lupus familis
XP_547953
806
90703
S773
S
S
E
S
S
H
S
S
S
S
H
S
H
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
R736
K
R
R
K
Q
K
L
R
S
A
A
A
S
R
R
Rat
Rattus norvegicus
Q63531
735
82865
Y702
K
G
G
M
A
A
T
Y
S
A
L
S
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S680
R
S
S
S
S
E
S
S
H
S
S
S
S
H
S
Chicken
Gallus gallus
Q5F3L1
789
89022
S756
S
S
E
S
S
H
S
S
S
S
H
S
H
G
K
Frog
Xenopus laevis
P10665
733
82620
Y700
K
G
A
M
A
A
T
Y
S
A
L
N
S
S
K
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
S706
G
A
M
A
A
T
Y
S
A
L
N
H
K
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S1061
S
V
A
T
Y
E
D
S
K
A
S
L
R
V
L
Honey Bee
Apis mellifera
XP_395099
910
102507
I850
Q
N
V
Q
C
T
E
I
Y
K
N
R
T
G
P
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
E730
N
S
R
V
T
Q
F
E
C
L
P
E
E
Q
E
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S726
E
S
T
H
S
Q
S
S
S
S
Q
E
S
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
P438
D
M
S
V
L
D
S
P
A
S
S
P
N
S
D
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
D644
K
P
I
D
S
V
V
D
E
Y
L
S
A
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
40
N.A.
0
0
N.A.
46.6
40
0
20
N.A.
6.6
0
6.6
60
P-Site Similarity:
100
100
100
40
N.A.
13.3
40
N.A.
53.3
40
46.6
46.6
N.A.
26.6
33.3
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
13
7
19
13
0
0
13
25
7
7
7
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
7
0
0
7
0
7
7
7
0
0
0
0
0
0
7
% D
% Glu:
25
0
13
0
0
13
7
7
7
0
0
13
7
0
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
13
7
0
0
0
0
0
0
0
0
19
0
19
0
% G
% His:
0
0
0
25
0
13
0
0
25
0
32
7
13
7
0
% H
% Ile:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
7
% I
% Lys:
25
0
0
7
0
7
0
0
7
7
0
0
25
0
25
% K
% Leu:
0
0
0
0
7
0
7
0
0
13
19
7
0
0
7
% L
% Met:
0
7
7
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
0
0
13
7
7
0
0
% N
% Pro:
0
7
0
0
0
0
0
7
0
0
7
7
0
0
7
% P
% Gln:
7
0
0
7
7
13
0
0
0
0
7
0
0
7
0
% Q
% Arg:
7
7
13
0
0
0
0
7
0
0
0
7
7
7
7
% R
% Ser:
19
50
32
19
50
19
50
57
38
50
19
32
32
25
7
% S
% Thr:
0
0
7
7
7
13
13
0
0
0
0
0
7
32
25
% T
% Val:
0
7
7
13
0
7
7
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
13
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _