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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
12.73
Human Site:
S783
Identified Species:
18.67
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S783
P
T
K
T
L
Q
P
S
N
P
A
D
S
N
N
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S875
P
T
K
T
L
Q
P
S
N
P
A
D
S
N
N
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S1035
P
T
K
T
L
Q
P
S
N
P
A
D
S
N
N
Dog
Lupus familis
XP_547953
806
90703
Q788
T
T
P
T
K
T
L
Q
P
S
H
P
A
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S751
G
S
P
V
P
A
S
S
G
R
L
P
A
S
A
Rat
Rattus norvegicus
Q63531
735
82865
I717
P
T
P
Q
L
K
P
I
E
S
S
I
L
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
K695
H
G
K
T
T
P
T
K
T
L
Q
P
T
N
P
Chicken
Gallus gallus
Q5F3L1
789
89022
Q771
T
T
P
T
K
T
L
Q
P
T
N
P
T
D
S
Frog
Xenopus laevis
P10665
733
82620
I715
P
T
P
L
L
Q
P
I
K
S
S
I
L
A
Q
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
A721
K
P
V
L
E
P
V
A
A
S
S
L
A
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
G1076
M
Q
Q
L
P
P
P
G
D
N
V
V
A
R
I
Honey Bee
Apis mellifera
XP_395099
910
102507
K865
V
T
R
S
R
K
R
K
L
E
E
Q
T
I
N
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
S745
A
E
M
T
S
S
T
S
R
P
S
N
L
G
M
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
V741
P
T
P
T
A
N
P
V
L
T
I
P
V
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
N453
A
K
A
N
P
F
T
N
F
T
Y
V
R
P
P
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
T659
Q
K
Q
F
G
G
W
T
Y
I
G
D
E
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
13.3
N.A.
6.6
26.6
N.A.
20
13.3
33.3
0
N.A.
6.6
13.3
20
26.6
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
40
N.A.
26.6
33.3
40
20
N.A.
26.6
40
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
0
7
7
0
7
7
0
19
0
25
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
0
25
0
13
0
% D
% Glu:
0
7
0
0
7
0
0
0
7
7
7
0
7
0
0
% E
% Phe:
0
0
0
7
0
7
0
0
7
0
0
0
0
0
0
% F
% Gly:
7
7
0
0
7
7
0
7
7
0
7
0
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
7
7
13
0
7
7
% I
% Lys:
7
13
25
0
13
13
0
13
7
0
0
0
0
0
0
% K
% Leu:
0
0
0
19
32
0
13
0
13
7
7
7
19
0
7
% L
% Met:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
7
0
7
0
7
19
7
7
7
0
25
25
% N
% Pro:
38
7
38
0
19
19
44
0
13
25
0
32
0
7
13
% P
% Gln:
7
7
13
7
0
25
0
13
0
0
7
7
0
13
13
% Q
% Arg:
0
0
7
0
7
0
7
0
7
7
0
0
7
7
7
% R
% Ser:
0
7
0
7
7
7
7
32
0
25
25
0
19
7
7
% S
% Thr:
13
57
0
50
7
13
19
7
7
19
0
0
19
7
7
% T
% Val:
7
0
7
7
0
0
7
7
0
0
7
13
7
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _