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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
5.45
Human Site:
S8
Identified Species:
8
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S8
M
E
E
E
G
G
S
S
G
G
A
A
G
T
S
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
A100
A
F
G
K
I
P
I
A
C
D
Y
R
T
D
Y
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S266
M
E
E
K
G
G
S
S
G
G
A
A
G
T
S
Dog
Lupus familis
XP_547953
806
90703
A15
R
A
Q
V
T
E
P
A
E
G
E
A
V
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
A11
E
D
E
D
E
G
C
A
V
E
L
Q
I
T
E
Rat
Rattus norvegicus
Q63531
735
82865
N22
L
V
P
L
D
P
E
N
G
Q
A
S
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
L8
M
H
A
V
T
V
T
L
K
S
E
D
D
A
I
Chicken
Gallus gallus
Q5F3L1
789
89022
T17
G
S
E
W
P
L
L
T
V
T
H
E
L
R
N
Frog
Xenopus laevis
P10665
733
82620
N22
V
V
H
E
D
P
E
N
G
H
G
S
P
E
E
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
K13
P
A
Q
E
S
S
L
K
M
E
V
Q
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
A191
S
K
A
K
S
N
N
A
A
A
A
A
A
A
A
Honey Bee
Apis mellifera
XP_395099
910
102507
E18
T
T
K
N
P
E
H
E
S
G
Y
F
E
D
G
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
M14
P
E
G
E
K
V
S
M
E
N
F
A
L
L
R
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
M11
A
Y
V
E
D
T
L
M
V
R
H
E
L
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
0
93.3
13.3
N.A.
20
20
N.A.
6.6
6.6
13.3
13.3
N.A.
13.3
6.6
26.6
6.6
P-Site Similarity:
100
13.3
100
33.3
N.A.
40
40
N.A.
13.3
20
33.3
20
N.A.
46.6
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
13
0
0
0
0
25
7
7
25
32
7
13
7
% A
% Cys:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
19
0
0
0
0
7
0
7
7
19
0
% D
% Glu:
7
19
25
32
7
13
13
7
13
13
13
13
7
13
19
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
7
0
13
0
13
19
0
0
25
25
7
0
19
0
7
% G
% His:
0
7
7
0
0
0
7
0
0
7
13
0
0
0
7
% H
% Ile:
0
0
0
0
7
0
7
0
0
0
0
0
7
0
7
% I
% Lys:
0
7
7
19
7
0
0
7
7
0
0
0
0
7
0
% K
% Leu:
7
0
0
7
0
7
19
7
0
0
7
0
19
7
0
% L
% Met:
19
0
0
0
0
0
0
13
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
7
7
13
0
7
0
0
0
0
13
% N
% Pro:
13
0
7
0
13
19
7
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
13
0
0
0
0
0
0
7
0
13
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
7
0
7
0
7
7
% R
% Ser:
7
7
0
0
13
7
19
13
7
7
0
13
7
0
19
% S
% Thr:
7
7
0
0
13
7
7
7
0
7
0
0
7
19
0
% T
% Val:
7
13
7
13
0
13
0
0
19
0
7
0
7
7
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
13
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _