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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
29.39
Human Site:
T194
Identified Species:
43.11
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
T194
S
N
G
H
V
V
L
T
D
F
G
L
S
K
E
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
T286
S
N
G
H
V
V
L
T
D
F
G
L
S
K
E
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
T452
S
N
G
H
V
V
L
T
D
F
G
L
S
K
E
Dog
Lupus familis
XP_547953
806
90703
T201
S
N
G
H
V
V
L
T
D
F
G
L
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
T200
R
T
F
S
F
C
G
T
I
E
Y
M
A
P
E
Rat
Rattus norvegicus
Q63531
735
82865
T204
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
R187
S
Q
A
E
I
S
R
R
I
L
K
S
E
P
P
Chicken
Gallus gallus
Q5F3L1
789
89022
I207
A
Y
S
F
C
G
T
I
E
Y
M
A
P
D
I
Frog
Xenopus laevis
P10665
733
82620
T204
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
T209
E
A
G
H
I
K
L
T
D
F
G
L
S
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S406
G
E
G
H
I
V
L
S
D
F
G
L
S
K
I
Honey Bee
Apis mellifera
XP_395099
910
102507
G212
H
I
V
L
T
D
F
G
L
S
K
E
F
L
P
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
R195
M
S
P
E
V
I
N
R
P
E
G
G
Y
S
D
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
V196
S
D
G
H
N
K
A
V
D
W
W
S
L
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
V172
Q
L
P
R
Y
K
R
V
D
Q
D
S
A
G
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
13.3
73.3
N.A.
6.6
0
73.3
73.3
N.A.
66.6
0
13.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
26.6
80
N.A.
13.3
20
80
80
N.A.
80
0
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
7
0
0
0
0
7
13
0
0
% A
% Cys:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
0
0
63
0
7
0
0
7
7
% D
% Glu:
19
19
0
13
0
0
0
0
7
13
0
7
7
0
57
% E
% Phe:
0
0
7
7
7
0
7
0
0
50
0
0
7
0
0
% F
% Gly:
7
0
57
0
0
7
7
7
0
0
57
7
0
13
0
% G
% His:
7
0
0
57
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
32
7
0
7
13
0
0
0
0
0
13
% I
% Lys:
0
0
0
0
0
32
0
0
0
0
13
0
0
50
0
% K
% Leu:
0
7
0
7
0
0
50
0
7
7
0
50
7
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
0
25
0
0
7
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
0
0
0
0
7
0
0
0
7
13
13
% P
% Gln:
7
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
7
0
0
7
0
0
13
13
0
0
0
0
0
0
0
% R
% Ser:
38
7
7
7
0
7
0
7
0
7
0
19
50
7
0
% S
% Thr:
0
7
0
0
7
0
7
50
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
32
32
0
13
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% W
% Tyr:
0
7
0
0
7
0
0
0
0
7
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _