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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
34.55
Human Site:
T669
Identified Species:
50.67
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
T669
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
T761
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
T921
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
Dog
Lupus familis
XP_547953
806
90703
T676
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
E645
E
A
W
Q
G
V
S
E
E
A
K
E
L
V
R
Rat
Rattus norvegicus
Q63531
735
82865
S599
D
E
G
C
D
I
W
S
L
G
V
L
L
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
T586
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
Chicken
Gallus gallus
Q5F3L1
789
89022
T659
E
L
I
Q
G
L
L
T
V
D
P
N
K
R
I
Frog
Xenopus laevis
P10665
733
82620
T604
S
L
G
I
L
L
Y
T
M
L
A
G
Y
T
P
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
F616
M
L
A
G
Y
T
P
F
A
N
G
P
N
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
Q868
H
L
V
S
W
C
L
Q
R
D
P
A
D
R
P
Honey Bee
Apis mellifera
XP_395099
910
102507
T688
V
D
P
S
K
R
L
T
A
N
G
L
A
N
H
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
T635
N
L
I
T
G
L
L
T
V
D
P
K
K
R
L
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
T629
D
L
I
K
G
L
L
T
V
D
P
S
R
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
I348
K
G
K
I
Q
Q
K
I
V
K
D
K
I
K
L
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
I554
V
P
V
M
Y
K
K
I
L
Q
Q
P
L
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
13.3
6.6
N.A.
100
86.6
20
6.6
N.A.
33.3
13.3
80
80
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
100
100
26.6
13.3
N.A.
40
20
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
13
7
7
7
7
0
0
% A
% Cys:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
44
7
0
0
7
0
0
0
0
57
7
0
7
7
0
% D
% Glu:
13
7
0
0
0
0
0
7
7
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
0
7
13
7
57
0
0
0
0
7
13
7
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
50
13
0
7
0
13
0
0
0
0
7
0
7
% I
% Lys:
7
0
7
7
7
7
13
0
0
7
7
13
44
7
0
% K
% Leu:
0
69
0
0
7
57
63
0
13
7
0
13
19
7
50
% L
% Met:
7
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
13
0
38
7
7
0
% N
% Pro:
0
7
7
0
0
0
7
0
0
0
57
13
0
0
13
% P
% Gln:
0
0
0
44
7
7
0
7
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
7
0
0
0
7
57
7
% R
% Ser:
7
0
0
13
0
0
7
7
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
7
0
7
0
63
0
0
0
0
0
7
13
% T
% Val:
13
0
13
0
0
7
0
0
57
0
7
0
0
7
0
% V
% Trp:
0
0
7
0
7
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
7
0
0
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _