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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
12.12
Human Site:
Y420
Identified Species:
17.78
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
Y420
M
M
K
D
S
P
F
Y
Q
H
Y
D
L
D
L
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
Y512
M
M
K
D
S
P
F
Y
Q
H
Y
D
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
M672
N
V
A
R
S
A
M
M
K
V
Y
R
C
D
L
Dog
Lupus familis
XP_547953
806
90703
Y427
M
M
K
D
S
P
F
Y
Q
H
Y
D
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
F405
M
M
Q
D
S
P
F
F
Q
Q
Y
E
L
D
L
Rat
Rattus norvegicus
Q63531
735
82865
H373
I
P
P
S
A
G
A
H
Q
L
F
R
G
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S355
P
L
G
E
G
S
F
S
I
C
R
K
C
L
H
Chicken
Gallus gallus
Q5F3L1
789
89022
F410
M
M
K
D
S
P
F
F
Q
H
Y
E
L
D
L
Frog
Xenopus laevis
P10665
733
82620
F381
Q
L
F
R
G
F
S
F
V
A
P
A
L
V
E
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
S385
H
Q
L
F
K
G
F
S
F
V
A
P
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
R628
D
D
L
E
L
G
T
R
T
S
N
G
A
Y
G
Honey Bee
Apis mellifera
XP_395099
910
102507
F445
R
F
E
E
S
T
F
F
Q
S
Y
E
I
D
L
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
A376
L
A
S
S
S
F
F
A
K
Y
K
L
D
K
S
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
N379
E
L
K
D
S
P
F
N
K
Y
Y
E
L
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
V134
S
P
E
E
V
S
G
V
V
G
I
E
D
F
E
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
S340
P
S
K
N
K
P
L
S
I
D
D
F
D
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
26.6
100
N.A.
73.3
6.6
N.A.
6.6
86.6
6.6
13.3
N.A.
0
40
13.3
53.3
P-Site Similarity:
100
100
40
100
N.A.
93.3
33.3
N.A.
20
100
20
20
N.A.
6.6
73.3
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
7
7
7
7
0
7
7
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
13
0
0
% C
% Asp:
7
7
0
38
0
0
0
0
0
7
7
19
19
50
0
% D
% Glu:
7
0
13
25
0
0
0
0
0
0
0
32
0
0
13
% E
% Phe:
0
7
7
7
0
13
63
25
7
0
7
7
0
13
0
% F
% Gly:
0
0
7
0
13
19
7
0
0
7
0
7
7
0
7
% G
% His:
7
0
0
0
0
0
0
7
0
25
0
0
0
0
7
% H
% Ile:
7
0
0
0
0
0
0
0
13
0
7
0
7
0
0
% I
% Lys:
0
0
38
0
13
0
0
0
19
0
7
7
0
7
0
% K
% Leu:
7
19
13
0
7
0
7
0
0
7
0
7
44
13
57
% L
% Met:
32
32
0
0
0
0
7
7
0
0
0
0
0
0
7
% M
% Asn:
7
0
0
7
0
0
0
7
0
0
7
0
0
0
0
% N
% Pro:
13
13
7
0
0
44
0
0
0
0
7
7
0
0
0
% P
% Gln:
7
7
7
0
0
0
0
0
44
7
0
0
0
0
0
% Q
% Arg:
7
0
0
13
0
0
0
7
0
0
7
13
0
0
0
% R
% Ser:
7
7
7
13
57
13
7
19
0
13
0
0
0
7
13
% S
% Thr:
0
0
0
0
0
7
7
0
7
0
0
0
0
0
0
% T
% Val:
0
7
0
0
7
0
0
7
13
13
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
13
50
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _